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Table 1 The correlation between clinical characteristics and dynamic change of the SII

From: Dynamic change of the systemic immune inflammation index is a risk factor for patients with oropharyngeal cancer: a case control study and an additional HPV-status subgroup analysis

Variables

Favorable (n = 53)

Unfavorable (n = 78)

Total (n = 131)

X2 or Z

p-value

Age, median (P25, P75)

56 (51.5, 66.5)

61 (51.0, 70.5)

 

1.304*

0.192

Gender, n (%)

 Female

15 (28.3)

22 (28.2)

37

0.000#

1.000

 Male

38 (71.7)

56 (71.8)

94

  

Nerve invasion (n, %)

 No

52 (98.1)

74 (94.9)

126

0.236#

0.627

 Yes

1 (1.9)

4 (5.1)

5

  

Vascular invasion (n, %)

 No

51 (96.2)

70 (89.7)

121

1.074#

0.300

 Yes

2 (3.8)

8 (10.3)

10

  

Cigarette smoking (n, %)

 No

22 (41.5)

31 (39.7)

53

0.041#

0.858

 Yes

31 (58.5)

47 (60.3)

78

  

Alcohol drinking (n, %)

 No

26 (54.7)

25 (44.9)

59

0.581#

0.478

 Yes

27 (50.9)

45 (57.7)

72

  

Tumor site (n, %)

 Tonsil

29 (54.7)

35 (44.9)

64

5.128#

0.077

 Tongue base

23 (43.4)

33 (42.3)

56

  

 Other+

1 (1.9)

10 (12.8)

11

  

Positive margin (n, %)

 No

14 (26.4)

26 (33.3)

40

1.202#

0.570

 Yes

1 (1.9)

3 (3.8)

4

  

 No-operation

38 (71.7)

49 (62.8)

87

  

Extranodal extension (n, %)

 No

13 (24.5)

23 (29.5)

36

0.560#

0.756

 Yes

4 (7.5)

7 (9.0)

11

  

 No-operation

36 (67.9)

48 (61.5)

84

  

Muscular/capsule invasion (n, %)

 No

6 (11.3)

21 (26.9)

27

4.696#

0.096

 Yes

10 (18.9)

12 (15.4)

22

  

 No-operation

37 (69.8)

45 (57.7)

82

  

Stage (n, %)

 I–II

10 (18.9)

13 (16.7)

23

0.106#

0.817

 III–IV

43 (81.1)

65 (83.3)

108

  

T stage (n, %)

 I–II

27 (50.9)

38 (48.7)

65

0.063#

0.806

 III–IV

26 (49.1)

40 (51.3)

66

  

N stage (n, %)

 N0

17 (32.1)

24 (30.8)

41

0.025#

1.000

 N+

36 (67.9)

54 (69.2)

90

  

Progression (n, %)

 No

26 (49.1)

23 (29.5)

49

5.162#

0.028

 Yes

27 (50.9)

55 (70.5)

82

  

Death (n, %)

 No

35 (66.0)

37 (47.4)

72

4.411#

0.049

 Yes

18 (34.0)

41 (52.6)

59

  
  1. +Including the pharyngolaryngeal fossa, the soft palate and the uvula; *Z-value; #Chi-square value. Both groups were comparable regarding these clinical characteristics including age, sex, nerve invasion, vascular invasion, cigarette smoking, alcohol drinking, positive margin, extranodal extension, muscular or capsule invasion, stage, T stage, N stage