Fig. 6

Screening and validation of potential biomarkers for the detection of HCM from key miRNAs. A ROC curves of the training set based on three ML (SVM, RF, LR) algorithms for distinguishing HCM patients from NCs. B ROC curves of the testing set based on the RF module. C ROC curves of external validation (GSE188324) based on the RF module. D Boxplot showing the expression levels of three miRNAs which were important variables based on RF in HCM patients and NCs. ^** and ^*** indicated P values < 0.01 and < 0.001. E ROC curves of experimental validation based on the RT-qPCR results of three miRNAs for distinguishing HCM patients from NCs