Table 1 Baseline characteristics of included patients
Variables | Localized | Regional | ||||
|---|---|---|---|---|---|---|
Patients, n | Deaths, n | SMR (95% CI) | Patients, n | Deaths, n | SMR (95% CI) | |
Total | 11,3734 | 30,390 | 1.59# (1.57–1.6) | 29,602 | 14,437 | 3.36# (3.31–3.42) |
Age | ||||||
15–44 years | 13,137 | 1,041 | 3.24# (3.04–3.44) | 1,843 | 607 | 17.15# (15.82–18.57) |
45–54 years | 22,692 | 3,265 | 2.44# (2.35–2.52) | 4,646 | 1,739 | 8.07# (7.7–8.46) |
55–64 years | 31,595 | 6,713 | 1.97# (1.93–2.02) | 7,958 | 3,361 | 5.04# (4.87–5.21) |
65–74 years | 27,606 | 8,969 | 1.51# (1.48–1.54) | 8,112 | 4,222 | 3.17# (3.07–3.26) |
75 + years | 17,619 | 10,361 | 1.27# (1.25–1.3) | 6,246 | 4,451 | 2.18# (2.12–2.25) |
Sex | ||||||
Male | 69,116 | 18,873 | 1.56# (1.54–1.59) | 19,456 | 9,371 | 3.22# (3.15–3.28) |
Female | 44,618 | 11,517 | 1.62# (1.59–1.65) | 10,146 | 5,066 | 3.67# (3.57–3.77) |
Year of diagnosis | ||||||
2000–2007 | 39,932 | 18,042 | 1.58# (1.55–1.6) | 11,362 | 7,905 | 3.16# (3.09–3.23) |
2008–2012 | 34,484 | 8,521 | 1.57# (1.54–1.61) | 8,553 | 4,133 | 3.43# (3.33–3.54) |
2013–2017 | 39,318 | 3,827 | 1.67# (1.61–1.72) | 9,687 | 2,399 | 4.10# (3.94–4.27) |
Race | ||||||
White | 92,846 | 24,884 | 1.52# (1.51–1.54) | 25,262 | 12,322 | 3.20# (3.15–3.26) |
Black | 14,168 | 4,073 | 1.86# (1.81–1.92) | 2,400 | 1,274 | 4.61# (4.36–4.87) |
American Indian-Alaska Native | 891 | 247 | 4.19# (3.69–4.75) | 237 | 97 | 6.43# (5.21–7.84) |
Asian or Pacific Islander | 5,829 | 1,186 | 2.04# (1.93–2.16) | 1,703 | 744 | 4.84# (4.5–5.21) |
Grade | ||||||
Well differentiated | 11,586 | 2,302 | 1.39# (1.33–1.45) | 1,102 | 465 | 2.11# (1.92–2.31) |
Moderately differentiated | 42,645 | 7,706 | 1.33# (1.3–1.36) | 7,879 | 3,059 | 2.15# (2.07–2.22) |
Poorly differentiated | 18,250 | 4,089 | 1.62# (1.57–1.67) | 9,432 | 4,718 | 3.60# (3.5–3.71) |
Undifferentiated | 3,213 | 1,147 | 2.48# (2.34–2.62) | 5,275 | 3,164 | 5.68# (5.48–5.88) |
Pathological type | ||||||
Papillary | 13,202 | 2,996 | 1.38# (1.33–1.43) | 1,691 | 758 | 2.91# (2.71–3.13) |
Chromophores | 6,352 | 908 | 0.92# (0.86–0.98) | 1,005 | 254 | 1.67# (1.47–1.88) |
Clear cell | 58,472 | 12,549 | 1.47# (1.45–1.5) | 14,201 | 5,660 | 2.85# (2.78–2.93) |
Surgical treatment | ||||||
Partial nephrectomy | 33,344 | 3,535 | 1.02 (0.99–1.06) | 2,339 | 569 | 1.60# (1.47–1.74) |
Radical nephrectomy | 48,672 | 11,929 | 1.61# (1.58–1.64) | 24,595 | 11,902 | 3.27# (3.21–3.33) |
Local tumor destruction | 5,983 | 1,527 | 1.35# (1.29–1.42) | 128 | 78 | 3.44# (2.72–4.29) |
Surgery, NOS | 933 | 260 | 1.63# (1.44–1.84) | 410 | 215 | 3.22# (2.81–3.69) |
No | 7,084 | 3,933 | 3.11# (3.01–3.21) | 1,551 | 1,328 | 9.84# (9.31–10.38) |
Chemotherapy | ||||||
Yes | 1,732 | 453 | 5.29# (4.81–5.8) | 3,562 | 1,841 | 8.96# (8.55–9.38) |
No/unknown | 112,002 | 29,937 | 1.57# (1.55–1.59) | 26,040 | 12,596 | 3.08# (3.03–3.14) |