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Table 2 Main causes of death for patients with localized kidney cancer

From: Second malignant tumors and non-tumor causes of death for patients with localized and regional kidney cancer after diagnosis

Causes of death

Total

Clear cell RCC

Non-clear cell RCC

Observed, n

Expected, n

SMR (95% CI)

Observed, n

Expected, n

SMR (95% CI)

Observed, n

Expected, n

SMR (95% CI)

All causes of death

30,390

19,151.73

1.59# (1.57–1.6)

12,549

8,512.19

1.47# (1.45–1.5)

17,841

10,639.55

1.68# (1.65–1.7)

All malignant cancers

12,022

4,575.66

2.63# (2.58–2.67)

5,118

2,095.27

2.44# (2.38–2.51)

6,904

2,480.39

2.78# (2.72–2.85)

Urinary system

7,500

260.56

28.78# (28.14–29.44)

3,267

117.66

27.77# (26.82–28.74)

4,233

142.9

29.62# (28.74–30.53)

 Kidney and renal pelvis

7,161

111.5

64.22# (62.74–65.73)

3,220

51.54

62.48# (60.34–64.67)

3,941

59.96

65.73# (63.69–67.81)

 Urinary bladder

277

141.91

1.95# (1.73–2.2)

44

62.87

0.70# (0.51–0.94)

233

79.03

2.95# (2.58–3.35)

Respiratory system

1,315

1,318.67

1 (0.94–1.05)

538

606.11

0.89# (0.81–0.97)

777

712.56

1.09# (1.02–1.17)

 Lung and bronchus

1,283

1,277.13

1 (0.95–1.06)

529

587.53

0.90# (0.83–0.98)

754

689.6

1.09# (1.02–1.17)

Digestive system

1,276

1,176.37

1.08# (1.03–1.15)

566

540.52

1.05 (0.96–1.14)

710

635.85

1.12# (1.04–1.2)

 Pancreas

393

308.78

1.27# (1.15–1.41)

174

143.53

1.21# (1.04–1.41)

219

165.25

1.33# (1.16–1.51)

 Colon and rectum

315

403.3

0.78# (0.7–0.87)

140

181.26

0.77# (0.65–0.91)

175

222.04

0.79# (0.68–0.91)

 Liver and intrahepatic bile duct

275

183.41

1.50# (1.33–1.69)

126

86.78

1.45# (1.21–1.73)

149

96.63

1.54# (1.3–1.81)

Male genital system

183

324.19

0.56# (0.49–0.65)

72

132.98

0.54# (0.42–0.68)

111

191.22

0.58# (0.48–0.7)

 Prostate

178

319.62

0.56#(0.48–0.65)

71

130.87

0.54# (0.42–0.68)

107

188.74

0.57# (0.46–0.69)

Brain and other nervous system

159

100.52

1.58#(1.35–1.85)

68

49.1

1.38# (1.08–1.76)

91

51.42

1.77# (1.42–2.17)

Leukemia

190

182.42

1.04 (0.9–1.2)

72

82.78

0.87 (0.68–1.1)

118

99.64

1.18 (0.98–1.42)

Lymphoma

148

173.82

0.85 (0.72–1)

62

79.52

0.78# (0.6–1)

86

94.3

0.91 (0.73–1.13)

Non-tumor causes

         

Diseases of heart

6,161

4,945.61

1.25# (1.21–1.28)

2,547

2,140.78

1.19# (1.14–1.24)

3,614

2,804.84

1.29# (1.25–1.33)

COPD and allied cond

1,185

1,194.07

0.99 (0.94–1.05)

470

543.39

0.86# (0.79–0.95)

715

650.67

1.10# (1.02–1.18)

Cerebrovascular diseases

1,183

1,058.31

1.12# (1.06–1.18)

480

455.48

1.05 (0.96–1.15)

703

602.83

1.17# (1.08–1.26)

Nephritis, nephrotic syndrome and nephrosis

1,166

387.89

3.01# (2.84–3.18)

409

165.73

2.47# (2.23–2.72)

757

222.16

3.41# (3.17–3.66)

Diabetes mellitus

1,137

595.36

1.91# (1.8–2.02)

488

265.59

1.84# (1.68–2.01)

649

329.77

1.97# (1.82–2.13)

Accidents and adverse effects

668

602.41

1.11# (1.03–1.2)

293

282.38

1.04 (0.92–1.16)

375

320.03

1.17# (1.06–1.3)

Alzheimer’s

611

701.64

0.87# (0.8–0.94)

242

300.21

0.81# (0.71–0.91)

369

401.43

0.92 (0.83–1.02)

Pneumonia and influenza

489

429.8

1.14# (1.04–1.24)

197

184.8

1.07 (0.92–1.23)

292

245

1.19# (1.06–1.34)

Hypertension without heart disease

482

223.68

2.15# (1.97–2.36)

192

96.06

2.00# (1.73–2.3)

290

127.62

2.27# (2.02–2.55)

Septicemia

406

285.54

1.42# (1.29–1.57)

164

125.48

1.31# (1.11–1.52)

242

160.05

1.51# (1.33–1.71)

Chronic liver disease and cirrhosis

293

220.44

1.33# (1.18–1.49)

149

110.01

1.35# (1.15–1.59)

144

110.44

1.30# (1.1–1.54)

Suicide and self-inflicted injury

151

153.78

0.98 (0.83–1.15)

83

78.18

1.06 (0.85–1.32)

68

75.61

0.9 (0.7–1.14)

  1. SMR standardized mortality ratio, CI confidence interval, COPD chronic obstructive pulmonary disease
  2. #Statistical significance with P < 0.05