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Table 3 Main causes of deaths for patients with regional kidney cancer

From: Second malignant tumors and non-tumor causes of death for patients with localized and regional kidney cancer after diagnosis

Causes of deaths

Total

Clear cell RCC

Non-clear cell RCC

Observed, n

Expected, n

SMR (95% CI)

Observed, n

Expected, n

SMR (95% CI)

Observed, n

Expected, n

SMR (95% CI)

All causes of death

14,437

4,292.43

3.36# (3.31–3.42)

5,660

1,983.35

2.85# (2.78–2.93)

8,777

2,309.08

3.80# (3.72–3.88)

All malignant cancers

10,352

1,016.84

10.18# (9.99–10.38)

3,918

487.27

8.04# (7.79–8.3)

6,434

529.57

12.15# (11.85–12.45)

Urinary system

8,746

61.07

143.22# (140.24–146.26)

3,423

29.15

117.44# (113.54–121.44)

5,323

31.92

166.77# (162.32–171.31)

Kidney and renal pelvis

8,240

25.34

325.20# (318.21–332.3)

3,410

12.36

275.95# (266.77–285.37)

4,830

12.98

372.08# (361.66–382.72)

Urinary bladder

371

34.05

10.90# (9.81–12.06)

10

15.99

0.63 (0.3–1.15)

361

18.06

19.99# (17.98–22.16)

Ureter

57

0.8

71.17# (53.91–92.21)

0

0.38

0 (0–9.7)

57

0.42

135.53# (102.65–175.59)

Respiratory system

354

295.99

1.20# (1.07–1.33)

145

142.81

1.02 (0.86–1.19)

209

153.19

1.36# (1.19–1.56)

Lung and bronchus

346

286.72

1.21# (1.08–1.34)

140

138.32

1.01 (0.85–1.19)

206

148.41

1.39# (1.2–1.59)

Digestive System

311

259.38

1.20# (1.07–1.34)

119

125.56

0.95 (0.79–1.13)

192

133.83

1.43# (1.24–1.65)

Pancreas

106

67.4

1.57# (1.29–1.9)

36

32.89

1.09 (0.77–1.52)

70

34.51

2.03# (1.58–2.56)

Colon and rectum

87

89.3

0.97 (0.78–1.2)

35

41.94

0.83 (0.58–1.16)

52

47.36

1.1 (0.82–1.44)

Liver and intrahepatic bile duct

48

39.77

1.21 (0.89–1.6)

23

20.15

1.14 (0.72–1.71)

25

19.61

1.27 (0.82–1.88)

Male genital system

46

78.63

0.59# (0.43–0.78)

18

35.37

0.51# (0.3–0.8)

28

43.26

0.65# (0.43–0.94)

Prostate

43

77.58

0.55# (0.4–0.75)

17

34.85

0.49# (0.28–0.78)

26

42.73

0.61# (0.4–0.89)

Soft tissue including heart

50

6.27

7.98# (5.92–10.51)

2

3.08

0.65 (0.08–2.35)

48

3.19

15.05# (11.1–19.96)

Brain and other nervous system

44

22

2.00# (1.45–2.68)

21

11.15

1.88# (1.17–2.88)

23

10.86

2.12# (1.34–3.18)

Leukemia

35

42.31

0.83 (0.58–1.15)

10

20.05

0.50# (0.24–0.92)

25

22.25

1.12 (0.73–1.66)

Lymphoma

29

40.39

0.72 (0.48–1.03)

13

19.15

0.68 (0.36–1.16)

16

21.24

0.75 (0.43–1.22)

Non-tumor causes

         

Diseases of heart

1,424

1,128.76

1.26# (1.2–1.33)

607

509.76

1.19# (1.1–1.29)

817

619

1.32# (1.23–1.41)

Cerebrovascular diseases

289

238.34

1.21# (1.08–1.36)

129

105.6

1.22# (1.02–1.45)

160

132.73

1.21# (1.03–1.41)

COPD and allied cond

266

274.97

0.97 (0.85–1.09)

104

129.15

0.81# (0.66–0.98)

162

145.82

1.11 (0.95–1.3)

Diabetes mellitus

227

129.1

1.76# (1.54–2)

112

60.84

1.84# (1.52–2.22)

115

68.25

1.68# (1.39–2.02)

Nephritis, nephrotic syndrome and nephrosis

210

85.61

2.45# (2.13–2.81)

90

38.64

2.33# (1.87–2.86)

120

46.97

2.56# (2.12–3.06)

Pneumonia and influenza

138

100

1.38# (1.16–1.63)

48

44.17

1.09 (0.8–1.44)

90

55.82

1.61# (1.3–1.98)

Alzheimer’s

130

159.43

0.82# (0.68–0.97)

60

69.31

0.87 (0.66–1.11)

70

90.13

0.78# (0.61–0.98)

Accidents and adverse effects

130

128.41

1.01 (0.85–1.2)

53

61.93

0.86 (0.64–1.12)

77

66.49

1.16 (0.91–1.45)

Septicemia

108

61.91

1.74# (1.43–2.11)

39

28.59

1.36 (0.97–1.86)

69

33.32

2.07# (1.61–2.62)

Hypertension without heart disease

89

47.89

1.86# (1.49–2.29)

37

21.55

1.72# (1.21–2.37)

52

26.34

1.97# (1.47–2.59)

Chronic liver disease and cirrhosis

65

45.89

1.42# (1.09–1.81)

35

24.07

1.45# (1.01–2.02)

30

21.82

1.37 (0.93–1.96)

Suicide and self-inflicted injury

33

32.71

1.01 (0.69–1.42)

15

17.1

0.88 (0.49–1.45)

18

15.62

1.15 (0.68–1.82)

  1. SMR standardized mortality ratio, CI confidence interval, COPD chronic obstructive pulmonary disease
  2. #Statistical significance with P < 0.05