Fig. 2

Time course of cytokine levels. The Kruskal–Wallis test followed by the Steel–Dwass test were used to compare time courses. The Wilcoxon test was used to compare the AN69ST- and PMMA-CRRT groups at each time point. No significant differences between the two groups were found at any time point. a: HMGB1, b: TNF-α, c: IL-6, d: IL-8, e: IL-10, f: IL-18, g: MIG, and h: MIP-1a. AN69ST polyethyleneimine-coated polyacrylonitrile, PMMA polymethylmethacrylate, CRRT continuous renal replacement therapy; HMGB-1 high-mobility group box 1, TNF-α tumor necrosis factor, IL interleukin, MIG monokine induced by interferon-γ, MIP macrophage inflammatory protein