Comparison of the cytokine adsorption ability in continuous renal replacement therapy using polyethyleneimine-coated polyacrylonitrile (AN69ST) or polymethylmethacrylate (PMMA) hemofilters: a pilot single-center open-label randomized control trial

Table 3 Secondary outcomes

Outcome	AN69ST (n = 26)	PMMA (n = 26)	AN69ST vs. PMMA
Outcome	AN69ST (n = 26)	PMMA (n = 26)	Unadjusted 95% CI	Adjusted ^a 95% CI	Unadjusted P value	Adjusted ^a P value
ICU mortality, n (%)	13 (50.0)	9 (34.6)	1.89 (0.62–5.76)	1.65 (0.48–5.85)	0.40	0.42
28-day all-cause mortality, n (%)	13 (50.0)	8 (30.8)	2.00 (0.67–6.23)	2.34 (0.67–8.72)	0.22	0.18
ICUFDs, median (IQR)	0 (0–18.3)	0 (0–16.0)	0.99 (0.93–1.05)	–	0.65	–
VAI at 48 h after CRRT initiation, median (IQR)	0 (0–8.4)	0 (0–15.0)	1.01 (0.99–1.05)	–	0.32	–
P/F ratio at 48 h after CRRT initiation, median (IQR)	220 (61.4–321.0)	227 (91.5–308)	1.00 (0.99–1.00)	–	0.71	–

AN69ST polyethyleneimine-coated polyacrylonitrile, PMMA polymethylmethacrylate, CI confidence interval, ICU intensive care unit, ICUFDs ICU-free days, IQR interquartile range; CRRT continuous renal replacement therapy, VAI vasopressor index, P/F partial pressure of arterial oxygen/fraction of inspired oxygen
^aAnalyzed by multilogistic regression model and explanatory variables such as age and SOFA score

ISSN: 2047-783X