Fig. 2

Comparison of lung tissue morphology, body weight and lung function of mice in each group. A The lung tissue of the control group mice is on the left, and the lung of the CS-induced COPD group mice is on the right. B Mouse weight changes during the experiments. C Forced vital capacity. D Functional residual capacity. E Resistance. F Chord compliance. G FEV50/FVC. n = 6 mice per group. Data are shown as the mean ± SEM (D) and median ± IQR (C, E–G). To test for group differences, Games–Howell (D) and Kurskal–Wallis (C, E–G). *p < 0.05, **p < 0.01, ***p < 0.001 versus control group, ^#p < 0.05, ^##p < 0.01, ^###p < 0.001 versus CS group