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Fig. 4 | European Journal of Medical Research

Fig. 4

From: Schisandrin A regulates the Nrf2 signaling pathway and inhibits NLRP3 inflammasome activation to interfere with pyroptosis in a mouse model of COPD

Fig. 4

SchA Ameliorates Inflammatory Cells and Factors in the BALF of CS-induced COPD Model Mice. A Representative images of leukocytes in BALF from each group (scale bar = 100 μm). B The numbers of total cells, macrophages and neutrophils in BALF. C The levels of IL-6, IL-1β and TNF-α in BALF were measured. n = 6 mice per group. Data are shown as the mean ± SEM (B Neutrophils and Macrophages in BALF, C) and median ± IQR (B Total cell counts in BALF). To test for group differences, Games–Howell (B Neutrophils and Macrophages in BALF, C IL-6 and TNF-α), Tukey (C IL-1β) and Kruskal‒Wallis (B Total cell counts in BALF) tests were used. *p < 0.05, **p < 0.01, ***p < 0.001 versus control group, #p < 0.05, ##p < 0.01, ###p < 0.001 versus CS group, +p < 0.05, ++p < 0.01, ++p < 0.001 versus CS + DEX group, §p < 0.05, §§p < 0.01, §§§p < 0.001 versus CS + SchA group

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