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Fig. 5 | European Journal of Medical Research

Fig. 5

From: Schisandrin A regulates the Nrf2 signaling pathway and inhibits NLRP3 inflammasome activation to interfere with pyroptosis in a mouse model of COPD

Fig. 5

SchA Treatment Reduces Oxidative Stress in CS-induced COPD Model Mice. The activity of A CAT and B SOD and the levels of C MDA in the right lung tissue. D The relative DHE fluorescence intensity in lung tissues in the different groups. E Representative images of lung sections stained with DHE (rad) and DAPI (blue) (scale bar = 50 μm). n = 6 mice per group. Data are shown as the mean ± SEM (B–D) and median ± IQR (A). To test for group differences, Games–Howell (B–D) and Kruskal‒Wallis (A) tests were used. *p < 0.05, **p < 0.01, ***p < 0.001 versus control group, #p < 0.05, ##p < 0.01, ###p < 0.001 versus CS group, +p < 0.05, ++p < 0.01, ++p < 0.001 versus CS + DEX group, §p < 0.05, §§p < 0.01, §§§p < 0.001 versus CS + SchA group

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