Fig. 3

DEGs identification and hub gene screening. A Lasso coefficient profile of tenfold cross-validation hub genes in the CD group. B Partial likelihood bias of log-change plotted by Lasso regression in tenfold cross-validation. A dashed vertical line is drawn at the optimal value with the minimum criterion (lambda. min) and 1 standard error of the minimum criterion (1-se criterion). C–H Boxplots of 6 hub genes in CD group and construction of ROC curve model (*p < 0.05; *p < 0.05; *p < 0.05, with an unpaired Student’s t test)