Fig. 4

The potential factors for tumor heterogeneity in the three subgroups. A–C The difference of copy number amplification or deletion in the three subgroups. The red represented the copy number amplification, and the blue represented the copy number deletion. D–F The alterations of gene expression levels in the three subgroups. The red solid circles represented the copy number amplification, and the blue solid circles represented the copy number deletion. G–I The specific distribution of copy number amplification and deletion as well as copy number variation-related genes in the three subgroups. J The Venn diagram showed that the remaining 26 DEGs also were not affected by CNVs in the genome