Fig. 9

Construction and evaluation of the comprehensive nomogram. A Univariate and multivariate Cox analyses of the risk score and clinical factors with OS. B The Schoenfeld residual suggested that this model met the equally PH assumption. C Comprehensive nomogram, including risk score, age and stage, was established to predict 1-, 3-, and 5-year OS probability in CCRCC. D The calibration curves of 1, 3, and 5 years showed more appropriate calibration ability. E The different score of nomogram in the three subgroups. F–H The DCA curves showed a comparable net benefit if the threshold probability for a patient or a doctor was within a range from 0 to 0.80 during 1, 3, and 5 years. I–K The time-dependent ROC curve analysis for the nomogram and single indicator during 1, 3, and 5 years, respectively