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Table 3 Results of the meta-analysis of intraoperative and recovery outcomes

From: Comparisons of perioperative and long-term outcomes of laparoscopic versus open gastrectomy for advanced gastric cancer after neoadjuvant therapy: an updated pooled analysis of eighteen studies

Pooled outcomes

Studies (n)

Sample size, n (LG:OG)

Effect size with 95% CI

P value

Heterogeneity (I2, %)

Publication bias (Begg’s Test)

Intraoperative outcomes

      

 Operative time, min (MD)

18

2096 (933:1163)

25.98 (18.42–33.53)

< 0.0001

78

0.820

 Estimated blood loss, ml (MD)

18

2096 (933:1163)

− 65.15 (− 91.02 to − 39.27)

< 0.0001

96

0.325

 Proximal margin, cm (MD)

5

364 (167:197)

− 0.26 (− 0.60 to 0.08)

0.13

0

–

 Distal margin, cm (MD)

5

364 (167:197)

− 0.20 (− 0.65 to 0.25)

0.38

0

–

 R1/R2 rate, n (OR)

10

1026 (484:542)

1.47 (0.67 to 3.20)

0.34

0

0.368

 Number of retrieved lymph nodes, n (MD)

16

1672 (832:840)

− 0.16 (− 1.43 to 1.10)

0.80

55

0.620

Postoperative recovery outcomes

      

 Time to first flatus, day (MD)

12

1240 (605:635)

− 0.56 (− 0.77 to − 0.35)

< 0.0001

66

0.062

 Time to first liquid intake, day (MD)

10

955 (473:482)

− 0.42 (− 0.76 to − 0.08)

0.02

53

0.371

 Time to remove gastric tube, day (MD)

3

452 (138:314)

− 0.73 (− 2.17 to 0.72)

0.32

69

–

 Time to remove drainage tube, day (MD)

4

317 (146:171)

− 0.69 (− 1.14 to 0.08)

0.08

0

–

 Postoperative hospital stay, day (MD)

18

2096 (933:1163)

− 2.26(− 3.60 to − 0.92)

 < 0.0001

97

0.363