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Table 1 Baseline characteristics

From: Association of the pretreatment lung immune prognostic index with immune checkpoint inhibitor outcomes in patients with advanced hepatocellular carcinoma

Characteristics

Total population

(N = 224)

LIPI 0

Good

(N = 80,35.7%)

LIPI 1

Intermediate

(N = 91, 40.6%)

LIPI 2

Poor

(N = 53, 23.7%)

P value

Age (years)

52.6 ± 10.5

53.1 ± 13.0

54.9 ± 8.8

53.3 ± 11.2

0.484

Gender

    

0.296

 Male

182(81.3%)

64(80.0%)

78(85.7%)

40(75.5%)

 

 Female

42(18.8%)

16(20.0%)

13(14.3%)

13(24.5%)

 

ECOG performance status

   

0.676

 0

152(67.2%)

57(71.3%)

61(67.0%)

34(64.2%)

 

 1

72(32.2%)

23(28.8%)

30(33.0%)

19(35.8%)

 

Child–Pugh stage

   

0.112

 A

159(71.0%)

65(81.3%)

58(63.7%)

36(67.9%)

 

 B

47(21.0%)

12(15.0%)

24(26.4%)

11(20.8%)

 

 C

18(8.1%)

3(3.8%)

9(9.9%)

6(11.3%)

 

HBV infection

   

0.562

 No

23(10.3%)

10(12.5%)

7(7.7%)

6(11.3%)

 

 Yes

201(89.7%)

70(87.5%)

84(92.3%)

47(88.7%)

 

Macrovascular invasion

   

0.165

 No

183(81.7%)

68(85.0%)

69(75.8%)

46(86.8%)

 

 Yes

41(18.3%)

12(15.0%)

22(24.2%0

7(13.2%)

 

AFP (ng/ml)

   

0.178

 < 400

93(42.3%)

32(41.0%)

33(37.1%)

28(52.8%)

 

 > 400

127(57.7%)

46(59.0%)

56(62.9%)

25(47.2)

 

Combined with target therapy

  

0.781

 Yes

112(50.0%)

39(48.8%)

48(52.7%)

25(47.2%)

 

 No

112(50.0%)

41(51.3%)

43(47.3%)

28(52.8%)

 
  1. ECOG Eastern Cooperative Oncology Group, BCLC Barcelona Clinic Liver Cancer, AFP a-fetoprotein, HBV hepatitis B virus, LIPI lung immune prognostic index