Table 2 Multivariate Cox model analysis for OS and PFS in the population

ECOG performance

 0

Ref

Ref

 ≥ 1

2.556 (1.784–3.663)

1.570 (1.163–2.119)

Child Pugh

 A

Ref

Ref

 B

1.990 (1.385–2.860)

1.843 (1.334–2.547)

 C

2.339 (1.872–2.409)

1.992 (1.492–2.672)

AFP

 ≤ 400

Ref

Ref

 > 400

1.252 (1.152–1.309)

1.679 (1.253–1.998)

HBV

 No

Ref

Ref

 Yes

1.967 (1.032–2.843)

1.769 (1.265–2.018)

Macrovascular Invasion

 No

Ref

Ref

 Yes

1.742 (1.139–2.664)

2.982 (1.279–4.671)

Combined with target therapy

 Yes

Ref

Ref

 No

2.493 (2.019–3.052)

2.835 (2.182–3.461)

LIPI

 Good

Ref

Ref

 Intermediate

2.181 (1.416–3.361)

1.872 (1.326–2.642)

 Poor

4.005 (2.467–6.501)

2.574 (1.717–2.857)