Table 3 Relationship between LIPI groups and response to Anti-PD-1 treatment
Response | No. of patients (%) | P value | |||
|---|---|---|---|---|---|
Overall n = 224 | LIPI good n = 80 | LIPI intermediate n = 91 | LIPI poor n = 53 | ||
CR | 0 (0) | 0 (0) | 0 (0) | 0 (0) | |
PR | 45 (20.1%) | 26 (32.5%) | 14 (15.4%) | 5 (9.4%) | |
SD | 105 (46.9%) | 47 (58.7%) | 39 (42.9%) | 19 (35.85%) | |
PD | 74 (33.0%) | 7 (8.8%) | 38 (41.8%) | 29 (54.7%) | |
ORR | 45 (20.1%) | 26 (32.5%) | 14 (15.4%) | 5 (9.4%) | 0.002 |
DCR | 150 (67.0%) | 73 (91.2%) | 53 (58.3%) | 24 (45.2%) | 0.000 |