Fig. 6

Definition of the Cuscore reliably predicting ccRCC prognosis. A Venn diagram shows the intersection of DEGs between cuproptosis subtypes in TCGA cohort. B GO and KEGG analysis results of cuproptosis-related genes. C PCA illustrates the discrimination of transcriptome profiling between low and high Cuscore groups in TCGA cohort. Each dot denotes a sample. D K-M curves of OS between groups in TCGA cohort. E ROC curves of 1-, 3- and 5-year OS based on the Cuscore in TCGA cohort. F Validation of the distinction of transcriptome profiling between low and high Cuscore groups in the E-MTAB-1980 cohort. G K-M curves of OS between groups in the E-MTAB-1980 dataset. H ROC curves of 1-, 3- and 5-year OS for the Cuscore in the E-MTAB-1980 cohort