Fig. 7

Associations of the Cuscore with clinicopathological features and definition of the Cuscore-based nomogram for prognostic prediction in TCGA cohort. A Clinicopathological features of low and high Cuscore groups. B–D Cuscore differences in distinct gender, grade, and stage. For asterisks, ns: p > 0.05; *p < 0.05; **p < 0.01; ***p < 0.001. E, F Uni- and multivariate Cox regression analysis of clinicopathological parameters and Cuscore on OS outcome. G–I Calibration curves show the consistency between the nomogram-predicted and actual prognostic outcome. J–L Decision curve analysis evaluates the net benefits of ccRCC patients from the nomogram, Cuscore and other clinicopathological parameters