Table 1 Baseline patient characteristics, overall and by ASPECTS determinations
Characteristic | Patients, No. (%) | |||
|---|---|---|---|---|
Overall (N = 343) | ASPECTS0–5 (n = 50) | ASPECTS 6–10 (n = 293) | P value | |
Age, y | 63.6 ± 12.6 | 61.1 ± 11.0 | 64.1 ± 12.8 | 0.058 |
Female | 104(30.3) | 9(18) | 95(32.4) | 0.044a |
Hypertension | 198(57.7) | 30(60) | 168(57.3) | 0.725 |
Diabetes mellitus | 90(26.2) | 11(22) | 79(27) | 0.410 |
Hyperlipidemia | 104(30.3) | 20(40) | 84(28.7) | 0.107 |
Atrial fibrillation/flutter | 133(38.3) | 20(40) | 113(38.6) | 0.848 |
Coronary artery disease | 67(19.5) | 8(16) | 59(20.1) | 0.495 |
Current/prior tobacco use | 162(47.2) | 27(54) | 135(46.1) | 0.300 |
Current/prior alcohol intake | 167(48.7) | 26(52) | 141(48.1) | 0.612 |
TOAST classification | 0.678 | |||
Large artery atherosclerosis | 256(74.6) | 36(72) | 220(75.1) | |
Cardioembolism | 79(23) | 12(24) | 67(22.9) | |
Other determined etiology | 8(2.3) | 2(4) | 6(2) | |
Prestroke | 77(22.4) | 11(22) | 66(22.5) | 0.934 |
Baseline NIHSS | 15.2 ± 4.5 | 18.1 ± 5.1 | 14.6 ± 4.3 | < 0.001a |
HMCAS | 211(61.5) | 39(78) | 172(58) | 0.010a |
Signs of early infarction | 215(62.7) | 45(90) | 170(58) | < 0.001a |
DBP on admission, mmHg | 82.8 ± 15.1 | 82.4 ± 14.6 | 82.9 ± 15.2 | 0.999 |
SBP on admission, mmHg | 140.5 ± 25.1 | 135.1 ± 27.2 | 141.4 ± 24.5 | 0.052 |
HbA1c, mmol/L | 6.3(5.7–8.0) | 6.7(5.7–8.0) | 6.3(5.7–8.0) | 0.354 |
D-dimer, mmol/L | 1.3(0.7–3.1) | 1.7(0.9–3.8) | 1.3(0.7–2.9) | 0.192 |
Occlusive location | 0.378 | |||
ICA | 91(26.5) | 17(34) | 74(25.3) | |
MCA M1 | 150(43.7) | 21(42) | 129(44) | |
MCA M2 | 22(6.4) | 1(2) | 21(7.2) | |
ICA + MCA | 80(23.3) | 11(22) | 69(23.5) | |
IV tPA | 82(23.9) | 7(14) | 75(25.6) | 0.760 |
Oneset to puncture, min | 412.0(233.5–609.0) | 422.5(280.7–545.5) | 410.0(227.0–615.0) | 0.918 |
Device passes | 1.5(1–2) | 1.5(1–2) | 1.5(1–2) | 0.255 |
Balloon-guided catheter | 80(23.3) | 10(20) | 70(23.9) | 0.548 |
Angioplasty and stenting | 26(7.6) | 4(8) | 22(7.5) | 0.903 |