Low (0–5) Alberta Stroke Program Early Computed Tomography Score on admission predictive of worse functional outcome after mechanical thrombectomy for anterior circulation large vessel occlusion

Table 3 Predictors of poor functional outcome at 90 days (univariate ordinal regression)

Characteristic	OR	95%CI	P value
Age, y	1.062	1.041–1.084	< 0.001^a
Female	1.30	0.818–2.067	0.267
Hypertension	1.136	0.740–1.745	0.559
Diabetes mellitus	2.574	1.545–4.287	< 0.001^a
Hyperlipidemia	0.790	0.498–1.252	0.315
Atrial fibrillation/flutter	1.531	0.987–2.373	0.057
Coronary artery disease	1.577	0.914–2.720	0.101
Current/prior tobacco use	0.715	0.467–1.094	0.122
Current/prior alcohol intake	0.669	0.437–1.025	0.065
TOAST classification	0.885	0.578–1.356	0.575
Large artery atherosclerosis
Cardioembolism
Other determined etiology
Prestroke	1.484	0.887–2.483	0.133
Baseline NIHSS score	1.143	1.082–1.208	< 0.001^a
HMCAS	0.857	0.554–1.326	0.489
Signs of early infarction	1.634	1.052–2.539	0.029*
DBP on admission	0.988	0.974–1.002	0.090
SBP on admission	0.997	0.988–1.005	0.461
HbA1c	1.486	1.279–1.728	< 0.001^a
D-dimer	1.144	1.040–1.259	0.006^a
Occlusive location	0.731	0.599–0.892	0.002^a
ICA
MCA M1
MCA M2
ICA + MCA
IV tPA	1.013	0.617–1.665	0.958
Oneset to puncture, min	0.999	0.999–1.000	0.086
Device passes	1.539	1.186–1.997	0.001^a
Balloon-guided catheter	0.783	0.474–1.292	0.338
Angioplasty and stenting	1.807	0.782–4.176	0.166
Successful reperfusion	0.324	0.189–0.555	< 0.001^a
Symptomatic ICH	1.782	1.080–2.941	0.024^a
ASPECTS ≤ 5	2.169	1.147–4.100	0.017^a

Significant values in bold
^aTOAST Trial of Org 10172 in Acute Stroke Treatment, NIHSS National Institutes of Health Stroke Scale, HMCAS hyperdense middle cerebral artery sign; DBP, diastolic blood pressure, SBP systolic blood pressure, HbA1c glycosylated hemoglobin, ICA internal carotid artery, MCA middle cerebral artery, IV tPA intravenous tissue plasminogen activator, ASPECTS Alberta Stroke Program Early CT Score

ISSN: 2047-783X