Table 3 The results of 24-h urine analysis and supersaturation indices of the study groups at baseline and the end of the treatment by vitamin D supplement (cholecalciferol)
Study groups | Time effect | Group effect | ||||||
|---|---|---|---|---|---|---|---|---|
2000/daily | 50,000/weekly | β (95% CI) | p- value | β (95% CI) | p- value | |||
Before | After | Before | After | |||||
24-U volume (mL/24 h) | 2098 (898) | 2414 (1094) | 1806 (687) | 2196 (768) | 357 (174, 539) | < 0.001*** | − 255 (− 653, 144) | 0.210 |
24-U creatinine (gr/24 h) | 1.18 (0.35) | 1.19 (0.35) | 1.16 (0.37) | 1.22 (0.31) | 0.03 (− 0.03, 0.10) | 0.296 | 0.003 (− 0.15, 0.16) | 0.966 |
24-U calcium (mg/24 h) | 160.29 (62.07) | 233.50 (64.90) | 155.26 (67.81) | 222.06 (93.56) | 69.70 (52.34, 87.06) | < 0.001*** | − 8.23 (− 39.18, 22.72) | 0.602 |
24-U sodium (meq/24 h) | 134.48 (74.83) | 154.90 (53.65) | 159.38 (64.41) | 156.29 (57.29) | 7.52 (− 11.32, 26.38) | 0.434 | 13.14 (− 11.21, 37.50) | 0.290 |
24-U potassium (meq/24 h) | 49.98 (16.71) | 53.07 (17.45) | 49.86 (24.77) | 57.08 (27.16) | 5.35 (− 0.98, 11.68) | 0.098 | 1.96 (− 6.72, 10.61) | 0.660 |
24-U phosphate (gr/24 h) | 0.66 (0.24) | 0.73 (0.26) | 0.65 (0.23) | 0.71 (0.28) | 0.06 (− 0.008, 0.13) | 0.085 | − 0.01 (− 0.11, 0.08) | 0.750 |
24-U magnesium (mg/24 h) | 64.47 (21.46) | 81.31 (34.14) | 65.41 (24.85) | 92.05(35.58) | 22.21 (14.03, 30.39) | < 0.001*** | 5.83 (− 6.24, 17.92) | 0.344 |
24-U citrate (mg/24 h) | 741.26 (352.89) | 810.64 (348.32) | 626.44 (337.74) | 891.38 (373.75) | 181.27 (99.33, 263.20) | < 0.001*** | − 11.89 (− 167.71, 143.92) | 0.881 |
24-U oxalate (mg/24 h) | 41.11 (15.71) | 43.90 (18.76) | 37.09 (15.98) | 43.00 (18.49) | 4.50 (0.14, 9.14) | 0.058 | − 2.46 (− 9.53, 4.60) | 0.494 |
24-U urea (gr/24 h) | 27.07 (9.04) | 30.63 (8.62) | 27.94 (9.71) | 30.59 (9.56) | 3.06 (0.44, 5.67) | 0.022* | 0.41 (− 3.26, 4.08) | 0.827 |
24-U uric acid (mg/24 h) | 431.54 (146.79) | 416.78 (139.60) | 467.09 (216.64) | 478.56 (175.28) | − 0.37 (− 46.56, 45.56) | 0.987 | 48.66 (− 22.44, 119.77) | 0.180 |
pH | 5.39 (0.83) | 5.50 (0.96) | 5.12 (0.48) | 5.38 (0.82) | 0.19 (− 0.05, 0.43) | 0.120 | − 0.19 (− 0.50, 0.10) | 0.207 |
CaOx SS | 5.52 (2.83) | 6.23 (2.13) | 5.27 (2.42) | 6.05 (2.60) | 0.74 (− 0.00, 1.50) | 0.052 | − 0.22 (− 1.19, 0.75) | 0.654 |
CaP SS | 0.58 (1.16) | 0.58 (1.19) | 0.20 (0.24) | 0.68 (1.45) | 0.26 (− 0.06, 0.58) | 0.110 | − 0.13 (− 0.59, 0.31) | 0.550 |