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Fig. 7 | European Journal of Medical Research

Fig. 7

From: MicroRNA-144-3p protects against chemotherapy-induced apoptosis of ovarian granulosa cells and activation of primordial follicles by targeting MAP3K9

Fig. 7

miR-144-3p protects GCs against cisplatin-induced apoptosis by targeting MAP3K9 via the p38 MAPK pathway. A Western blotting to detect the protein levels of cleaved caspase-3 and p38 MAPK pathway-related molecules in cisplatin injured COV434 cells. B Western blotting to determine the level of MAP3K9 in COV434 cells transfected with MAP3K9 siRNA and scrambled control oligonucleotide. C Cleaved caspase-3 and p38 MAPK pathway-related proteins levels were analyzed by western blotting in miR-144-3p antagomir and MAP3K9 siRNA co-treated COV434 cells. GCs, granulosa cells. *P < 0.05; **P < 0.01, two-tailed Student’s t test

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