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Fig. 8 | European Journal of Medical Research

Fig. 8

From: MicroRNA-144-3p protects against chemotherapy-induced apoptosis of ovarian granulosa cells and activation of primordial follicles by targeting MAP3K9

Fig. 8

miR-144-3p attenuates cisplatin-induced primordial follicle activation via MAP3K9 in mouse ovaries in vivo. A Western blotting detection of MAP3K9 and PI3K/AKT pathway-related proteins in mice. B H&E staining displaying ovarian morphology and columns representing the proportion of follicles at various stages of development in mice. Control group, n = 3; POF + agomir NC group, n = 3; POF + agomir group, n = 3. H&E: hematoxylin and erosion; POF: premature ovarian failure. *P < 0.05; **P < 0.01, two-tailed Student’s t test

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