Fig. 1
From: KL is a favorable prognostic factor related immune for clear cell renal cell carcinoma
Illustrates the volcano plots of DEGs (differentially expressed genes) between normal renal tissues and renal cancer in GSE168845 samples (A). A total of 3097 DEGs were identified, with 1288 being upregulated and 1809 downregulated genes, meeting the criteria of adjusted p < 0.05 and log2-fold change (absolute) > 1, The upregulated genes are highlighted in red, while the downregulated genes are depicted in blue. To further investigate immune-related genes (IRGs) and age-related genes (AGs), 1793 human IRGs were downloaded from IMMPORT DATABASE, and 368 human AGs were obtained from Msigdb (https://www.gsea-msigdb.org/gsea/msigdb/index.jsp/). A Venn diagram was generated to show the 17 immune-aging genes shared by the three datasets (B). Finally, the GO and KEEG analysis of the 17 immune-aging genes was illustrated in a graph (C)