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Table 2 The biochemical parameters in T2DM patients with/ without CAD

From: Protective effects of paraoxonase-1, vitamin E and selenium, and oxidative stress index on the susceptibility of low density lipoprotein to oxidation in diabetic patients with/without coronary artery disease

 

T2DM (M ± SD)

(n = 41)

T2DM patients with CAD(M ± SD) (n = 41)

P value

HbA1c (%)

7.46 ± 1.22

8.12 ± 1.18

0.015

FBG (mg/dl)

155.70 ± 43.82

145.64 ± 26.92

0.214

TC(mg/dl)

158.03 ± 40.41

170.68 ± 33.43

0.127

TAC (μmol Trolox equiv./l)

1.18 ± 0.30

0.87 ± 0.24

0.000

TOS (µmol H2O2equiv/l)

0.64 ± 0.49

1.4 ± 0.9

0.000

OSI (TOS/TAC)

0.60 ± 0.53

1.73 ± 1.22

0.000

MDA(mmol/l)

21 ± 3.18

26.76 ± 6.97

0.000

PON1 activity

48.29 ± 11.47

39.76 ± 14.03

0.003

Ox-LDL(ng/ml)

1276.56 ± 271.31

1498.17 ± 159.82

0.000

Vitamin E (U/ml)

4.61 ± 2.01

2.65 ± 0.84

0.000

Selenium (ppb)

24.08 ± 6.80

18.64 ± 6.38

0.000

  1. Data are presented as mean value and standard deviation (SD); indicator the presence or absence of a significant difference between the values of similar variables in the two groups (P value). Type 2 diabetes mellitus (T2DM); coronary artery disease (CAD); fasting blood glucose (FBG); hemoglobin A1C (HbA1c); total cholesterol (TC); total antioxidant capacity (TAC); total oxidant power (TOS); malondialdehyde (MDA); vitamin E; selenium (Se); oxidized low density lipoprotein (Ox-LDL); paraoxonases-1 (PON1)