Fig. 5

Resveratrol modulates the arginine/proline metabolic pathway. A Hierarchical clustering heatmap of significantly differential metabolites in negative ion mode. B Hierarchical clustering heatmap of significantly differential metabolites in positive ion mode. C Differential metabolite network diagram between the RSV group and the DSS group in positive ion mode. D KEGG enrichment pathway diagram (bubble diagram). E Differential abundance score plot of all enriched metabolic pathways between the RSV group and the DSS group. F Clustering heatmap of differential metabolites in the KEGG pathway for arginine and proline metabolism between the DSS and the RSV groups. G KEGG pathway diagram of arginine and proline metabolism containing differential metabolites