Table 4 The detailed demographic characteristics of the populations diagnosed and classified by the NINCDS-ADRDA criteria in ADNI
Characteristicsab | Total sample (n = 1289) | Sub-sample (n = 1111) | CN (n = 571) | MCI (n = 540) | AD (n = 178) |
|---|---|---|---|---|---|
Age (years, Mean ± SD) | 73.87 ± 5.85 | 73.40 ± 5.71 | 72.36 ± 5.62 | 74.51 ± 5.60 | 76.78 ± 5.92 |
Gender (N/%) | |||||
 Female | 618 (47.94) | 561 (50.50) | 327 (57.27) | 223 (41.30) | 68 (38.20) |
 Male | 671 (52.06) | 550 (49.50) | 244 (42.73) | 317 (58.70) | 110 (61.80) |
 Education (years, Mean ± SD) | 16.36 ± 2.53 | 16.46 ± 2.50 | 16.74 ± 2.36 | 16.18 ± 2.61 | 15.70 ± 2.63 |
Ethnical classification (N,%) | |||||
 Hispanic/Latino | 68 (5.28) | 60 (5.40) | 33 (5.78) | 27 (5.00) | 8 (4.49) |
 Not Hispanic/Latino | 1216 (94.34) | 1047 (94.24) | 535 (93.70) | 512 (94.81) | 169 (94.95) |
 Unknown | 5 (0.38) | 4 (0.36) | 3 (0.52) | 1 (0.19) | 1 (0.56) |
Racial classification (N,%) | |||||
 White | 1138 (88.29) | 977 (87.94) | 492 (86.16) | 485 (89.82) | 161 (90.45) |
 Black | 93 (7.21) | 82 (7.38) | 51 (8.93) | 31 (5.74) | 11 (6.18) |
 Asian | 28 (2.17) | 23 (2.07) | 15 (2.63) | 8 (1.48) | 5 (2.81) |
 Others | 30 (2.33) | 29 (2.61) | 13 (2.28) | 16 (2.96) | 1 (0.56) |
Marriage state (N,%) | |||||
 Married | 964 (74.79) | 809 (72.82) | 403( 70.58) | 406 (75.19) | 155 (87.08) |
 Widowed | 146 (11.33) | 129 (11.61) | 73 (12.78) | 56 (10.37) | 17 (9.56) |
 Divorced | 127 (9.85) | 124 (11.16) | 72 (12.61) | 52 (9.63) | 3 (1.68) |
 Never married | 45 (3.49) | 42 (3.78) | 22 (3.85) | 20 (3.70) | 3 (1.68) |
 Unknown | 7 (0.54) | 7 (0.63) | 1 (0.18) | 6 (1.11) | 0 |
MMSE(Mean ± SD) | 27.70 ± 2.56 | 28.44 ± 1.66 | 29.03 ± 1.19 | 27.81 ± 1.85 | 23.06 ± 2.33 |
MoCA(Mean ± SD) | 23.46 ± 4.20 | 24.48 ± 3.19 | 25.88 ± 2.53 | 23.00 ± 3.14 | 17.14 ± 4.26 |
ADAS-cog (Mean ± SD) | 9.36 ± 6.39 | 7.60 ± 4.21 | 5.60 ± 2.87 | 9.71 ± 4.38 | 20.36 ± 6.67 |