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Fig. 2 | European Journal of Medical Research

Fig. 2

From: Impaired autophagy contributes to the aggravated deterioration of osteoarthritis articular cartilage by peroxisome proliferator-activated receptor α deficiency, associated with decreased ERK and Akt activation

Fig. 2

Expression of ECM synthesis biomarkers in cartilage of PPARα-KO mouse model of experimental OA. Sections in different treated groups were examined using immunohistochemistry assay; A representative image from mice of different treated groups expressing Aggrecan (original magnification × 40). Graph shows the relative area expressing Aggrecan. Data are mean ± SD of 24 fields of vision per group (*p < 0.05); B representative images from mice of different treated groups expressing Collagen II (original magnification × 40). Graph shows the relative area expressing Collagen II. Data are mean ± SD of 24 fields of vision per group (*p < 0.05)

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