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Table 2 Metabolic indexes, ovarian function and ART outcomes of two study groups

From: Effects of dysregulated glucose metabolism on the occurrence and ART outcome of endometriosis

Characteristics

Endometriosis

(n = 412)

Controls

(n = 1551)

P value

Basal E2 (pmol/L)

114.65 (67.97–156.58)

110.70 (67.70–153.60)

0.405

Basal P (nmol/L)

1.14 (0.75–1.55)

1.12 (0.76–1.50)

0.644

Basal T (nmol/L)

0.50 (0.00–0.80)

0.60 (0.00–0.90)

0.005

Glu (mmol/L)

5.01 (4.79–5.27)

5.04 (4.80–5.31)

0.134

INS (μU/mL)

6.90 (5.10–9.50)

6.50 (4.80–8.90)

0.005

TG (mmol/L)

0.92 (0.71–1.19)

0.92 (0.69–1.27)

0.435

TC (mmol/L)

4.35 (3.92–4.80)

4.27 (3.81–4.77)

0.036

HDL-C (mmol/L)

1.36 (1.19–1.57)

1.32 (1.14–1.52)

0.005

LDL-C (mmol/L)

2.63 (2.17–3.01)

2.54 (2.12–2.94)

0.043

TP (g/L)

71.97 ± 4.49

72.20 ± 4.77

0.318

ALT (U/L)

13.00 (10.00–17.00)

13.00 (10.00–18.00)

0.178

AST (U/L)

17.00 (15.00–20.00)

18.00 (15.00–20.00)

0.068

Creatinine (μmoI/L)

56.00 (50.00–62.60)

55.10 (49.00–62.00)

0.202

Urea nitrogen (mmol/L)

3.78 (3.21–4.48)

3.76 (3.18–4.51)

0.621

Uric acid (μmoI/L)

266.00 (234.25–303.00)

270.00 (231.00–312.00)

0.277

HCY (nmol/L)

9.70 (8.50–10.80)

9.80 (8.50–11.10)

0.281

AMH (ng/mL)

2.02 (1.06–3.49)

2.53 (1.48–4.07)

 < 0.001

AFC (n)

8.00 (5.00–11.00)

10.00 (7.00–12.00)

 < 0.001

Basal FSH (IU/L)

6.74 (5.26–8.35)

6.32 (4.81–7.87)

 < 0.001

Basal LH (IU/L)

4.19 ± 2.40

4.60 ± 2.66

0.031

Gn dosage (IU)

2025.00 (1575.00–2700.00)

2025.00 (1575.00–2475.00)

0.664

Gn days (day)

9.00 (8.00–12.00)

9.00 (8.00–11.00)

0.058

Number of retrieved oocytes (n)

7.00 (4.00–11.00)

9.00 (5.00–14.00)

 < 0.001

Fertilization rate [%]

64.3 (2158/3357)

64.0 (9714/15172)

0.778

Cleavage rate [%]

23.7 (512/2158)

24.1 (2338/9714)

0.736

Number of transferable embryos (n)

0.76 ± 0.93

0.77 ± 0.93

0.776

Number of high-quality embryos (n)

0.57 ± 0.82

0.60 ± 0.83

0.402

High-quality embryos rate [%]

12.1 (232/1912)

11.1 (936/8435)

0.196

Number of embryos transferred (n)

1.81 ± 0.39

1.78 ± 0.41

0.389

Implantation rate1 [%]

38.7 (122/315)

36.0 (429/1191)

0.375

Ectopic pregnancy rate2 [%]

2.3 (4/174)

1.5 (10/669)

0.684

Clinical pregnancy rate3 [%]

51.7 (90/174)

49.5 (331/669)

0.597

Miscarriage rate4 [%]

6.9 (12/174)

5.7 (38/669)

0.606

Delivery rate5 [%]

45.4 (79/174)

43.8 (293/669)

0.606

Live birth rate6 [%]

54.0 (94/174)

54.0 (361/669)

0.988

  1. Values are expressed as mean ± standard deviation, median (interquartile range) or number (%)
  2. E2 estradiol, P progesterone, T testosterone, Glu glucose, INS insulin, TG triglycerides, TC total cholesterol, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol, TP total protein, ALT alanine aminotransferase, AST aspartate aminotransferase, HCY homocysteine, AMH anti-Müllerian hormone, AFC antral follicle counting, FSH follicle stimulating hormone, LH luteinizing hormone, Gn gonadotropin. 1. Implantation rate: the ratio of the number of gestational sacs to the total number of embryos transferred. 2. Ectopic pregnancy rate: the ratio of the number of Ectopic pregnancy cycles to the total number of transfer cycles. 3. Clinical pregnancy rate: the ratio of the number of clinical pregnancy cycles to the total number of transfer cycles. 4. Miscarriage rate: the ratio of the number of miscarriage cycles to the total number of transfer cycles. 5. Delivery rate: the ratio of the number of deliveries that resulted in at least one live born baby to the total number of transfer cycles. 6. Live birth rate: the ratio of the number of live born babies to the total number of live born babies
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European Journal of Medical Research

ISSN: 2047-783X

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