Table 3 Univariate and multivariate Cox analyses for OS of UTUC patients

Sex

 Female

Reference

 Male

1.257

0.938–1.683

Age

  < 65

Reference

Reference

  ≥ 65

1.681

1.189–2.376

1.509

BMI

  < 25

Reference

  ≥ 25

0.936

0.695–1.260

Side

 Left

Reference

 Right

1.019

0.760–1.367

Site

 Pelvis

Reference

Reference

 Ureter

1.413

1.036–1.928

1.244

 Both

1.037

0.571–1.883

0.685

Approach

 Open

Reference

 Laparoscopic

1.132

0.836–1.532

Ureteroscopy

 No

Reference

Reference

 Yes

1.620

1.101–2.384

1.171

Hydronephrosis

 No

Reference

Reference

 Yes

1.904

1.285–2.821

1.217

Multifocality

 No

Reference

 Yes

1.318

0.909–1.911

Size

  < 5

Reference

Reference

  ≥ 5

1.744

1.181–2.574

1.205

LVI

 No

Reference

Reference

 Yes

3.766

2.668–5.316

1.979

Tis

 No

Reference

 Yes

1.018

0.520–1.992

T stage

 T1

Reference

Reference

 T2

2.507

1.551–4.052

1.804

 T3

3.404

2.155–5.376

2.334

 T4

12.446

6.821–22.709

3.633

Margin

 Negative

Reference

Reference

 Positive

5.062

2.648–9.678

2.999

N stage

 pN0&Nx

Reference

Reference

 pN + 

5.344

3.583–7.972

2.191

Grade

 Low

 High

2.013

1.354–2.993

1.357

Chemotherapy

 No

Reference

Reference

 Yes

2.241

1.611–3.116

1.274

SOSI

 Low risk

Reference

Reference

 High risk

2.217

1.577–3.117

1.656