Table 1 Baseline characteristics
Characteristics | ALL (N = 922) N (%) | CRT (N = 497) N (%) | CT (N = 425) N (%) | p-value |
|---|---|---|---|---|
Age | 0.158a | |||
< 60 | 286 (31.0%) | 161 (32.4%) | 125 (29.4%) | |
≥ 60 | 636 (69.0%) | 336 (67.6%) | 300 (70.6%) | |
Sex | 0.096 | |||
Female | 476 (51.6%) | 244 (49.1%) | 232 (54.6%) | |
Male | 446 (48.4%) | 253 (50.9%) | 193 (45.4%) | |
Primary tumor site | < 0.001b | |||
Intrahepatic bile duct | 139 (15.1%) | 40 (8.0%) | 99 (23.3%) | |
Extrahepatic bile duct | 364 (39.5%) | 218 (43.9%) | 146 (34.4%) | |
Gallbladder | 419 (45.4%) | 239 (48.1%) | 180 (42.4%) | |
T stage | 0.058 | |||
T1 | 110 (11.9%) | 47 (9.5%) | 63 (14.8%) | |
T2 | 330 (35.8%) | 186 (37.4%) | 144 (33.9%) | |
T3 | 377 (40.1%) | 211 (42.5%) | 166 (39.1%) | |
T4 | 105 (11.4%) | 53 (10.7%) | 52 (12.2%) | |
N stage | 0.046 | |||
N0 | 493 (53.5%) | 247 (49.7%) | 246 (57.9%) | |
N1 | 422 (45.8%) | 246 (49.5%) | 176 (41.4%) | |
Nx | 7 (0.7%) | 4 (0.8%) | 3 (0.7%) | |
Tumor size | 0.059 | |||
< 5 cm | 598 (64.9%) | 336 (67.6%) | 262 (61.6%) | |
≥ 5 cm | 324 (35.1%) | 161 (32.4%) | 163 (38.4%) | |
# of removed lymph nodes | 0.046 | |||
0 | 212 (23.0%) | 97 (19.5%) | 115 (27.1%) | |
1–3 | 287 (31.1%) | 163 (32.8%) | 124 (29.2%) | |
≥ 4 | 404 (43.8%) | 228 (45.9%) | 176 (41.4%) | |
NA | 19 (2.1%) | 9 (1.8%) | 10 (2.4%) | |
Grade | 0.101 | |||
I: Well differentiated | 104 (11.3%) | 60 (12.1%) | 44 (10.4%) | |
II: Moderately differentiated | 405 (43.9%) | 230 (46.3%) | 175 (41.2%) | |
III: Poorly differentiated | 312 (33.8%) | 159 (32.0%) | 153 (36.0%) | |
IV: Undifferentiated; anaplastic | 20 (2.2%) | 13 (2.6%) | 7 (1.6%) | |
NA | 81 (8.8%) | 35 (7.0%) | 46 (10.8%) |