Fig. 3

Hexarelin mitigates cell damage after H/R exposure. A In vitro experiments were conducted using HK-2 cells administrated with different concentrations of Hexarelin before hypoxia for 9 h followed by Reoxygenation for 3 h; B qRT-PCR used to measure the relative expression of Hif-1α; C cell viability was detected using CCK-8 assay; D mRNA level of KIM-1 after Hexarelin administration followed by H/R treatment. *P < 0.05, **P < 0.01 versus control; ^#P < 0.05, ^##P < 0.01 versus AKI