Fig. 4
From: Hexarelin alleviates apoptosis on ischemic acute kidney injury via MDM2/p53 pathway
Hexarelin inhibited apoptosis in H/R-induced HK-2 cell. A Cell apoptosis of (I) H/R, pretreated with Hexarelin at a dose of (II)10–6, (III) 10–5 (IV) 10–4 were measured via PI staining; B relative fluorescent intensity of control, H/R, Hexarelin pretreatment before H/R and PBS pretreatment before H/R groups; C–F mRNA level of Caspase-3, Bax, Bad and Bcl-2 measured by qRT-PCR; G–K protein level of Caspase-3, Bax, Bad and Bcl-2 detected by Western blot analysis. *P < 0.05, **P < 0.01 versus control; #P < 0.05, ##P < 0.01 versus AKI