Characteristics | Controls N = 28,990 | IBD Cases N = 2899 | p-value | IBD Cases | p-value | |
---|---|---|---|---|---|---|
CD (N = 828) | UC (N = 2071) | |||||
Sex | ||||||
Males | 18,510 (63.85) | 1851 (63.85) | 1.000 | 563 (68.00) | 1288 (62.19) | 0.003 |
Females | 10,480 (36.15) | 1048 (36.15) | 265 (32.00) | 783 (37.81) | ||
Age (years), mean ± SD | 41.10±15.83 | 41.10±15.83 | 36.83±16.60 | 42.80±15.18 | ||
> 12–18 | 1890 (6.52) | 189 (6.52) | 1.000 | 98 (11.84) | 91 (4.39) | < 0.001 |
19 to < 40 | 12,520 (43.19) | 1252 (43.19) | 422 (50.97) | 830 (40.08) | ||
40 to < 60 | 10,800 (37.25) | 1080 (37.25) | 210 (25.36) | 870 (42.01) | ||
≥ 60 | 3780 (13.04) | 378 (13.04) | 98 (11.84) | 280 (13.52) | ||
Monthly insured salary, USD | ||||||
< 700 (median) | 11,945 (43.38) | 1052 (37.37) | < 0.001 | 275 (34.16) | 777 (38.66) | 0.026 |
≥ 700 (median) | 15,591 (56.62) | 1763 (62.63) | 530 (65.84) | 1233 (61.34) | ||
Median annual family-income in areas of residence (USD) a | ||||||
< 17,000 (Q1) | 6594 (24.82) | 675 (25.26) | 0.021 | 178 (23.30) | 497 (26.05) | 0.506 |
17,000 (Q1) to < 18,600 (Q2) | 6629 (24.95) | 631 (23.62) | 188 (24.61) | 443 (23.22) | ||
18,600 (Q2) to < 20,600 (Q3) | 6717 (25.28) | 635 (23.76) | 183 (23.95) | 452 (23.69) | ||
≥ 20,600 (Q3) | 6628 (24.95) | 731 (27.36) | 215 (28.14) | 516 (27.04) | ||
IGE ever occurred in 5 time-windows | ||||||
≤ 1 year | 1026 (3.54) | 609 (21.01) | < 0.001 | 199 (24.03) | 410 (19.80) | 0.011 |
> 6 months–1 year | 543 (1.87) | 161 (5.55) | < 0.001 | 59 (7.13) | 102 (4.93) | 0.020 |
> 1–3 years | 1794 (6.19) | 377 (13.00) | < 0.001 | 149 (18.00) | 228 (11.01) | < .001 |
> 3–5 years | 1638 (6.77) | 227 (9.38) | < 0.001 | 80 (11.08) | 147 (8.66) | 0.061 |
> 6 months–5 years | 3048 (12.60) | 520 (21.49) | < 0.001 | 203 (28.12) | 317 (18.67) | < 0.001 |