Bidirectional association between infectious gastroenteritis and inflammatory bowel disease: a population-based study

Table 4 Incidence rate of IGE episodes before and after IBD diagnosis in IBD cases and controls

	Controls			IBD cases
	Before	After	p-value	Before	After	p-value
Mean number of IGE episodes	0.56 ± 2.48	0.32 ± 1.64	< 0.001	1.39 ± 3.40	1.83 ± 6.45	< 0.001
Total number of IGE episodes	16,152	9271		4022	5295
Observed person-years	289,742.9	170,520.6		28,974.3	16,957.9
Incidence rate, per 1000 person-years	55.7	54.4		138.8	312.2
Crude IRR (95% CI)	Ref.	0.98 (0.95, 1.00)	0.055	Ref.	2.25 (2.16-2.34)	< 0.001
Adjusted IRR (95% CI)^a	Ref.	Ref.		2.42 (2.34–2.51)^b	5.74 (5.54–5.95)^c

IGE infective gastroenteritis. IRR incidence rate ratio. Ref. reference group
^aAdjusted for monthly insured salary, median annual family-income level, urbanization level, Charlson’s comorbidity index, any history of selected immune-related disease
^bcompared to incidence rate of controls before the index date (p< 0.001)
^ccompared to incidence rate of controls after the index date (p< 0.001)

ISSN: 2047-783X