Table 3 Univariate and multivariate cox proportional hazard model of gastric cancer with DFS

Age (year)

  < 60

1

  ≥ 60

1.13 (0.91–1.39)

Sex

 Male

1

 Female

0.71 (0.56–0.91)

Tumor location

 Upper third

1

 Middle third

0.97 (0.74–1.26)

 Lower third

0.82 (0.64–1.05)

 Diffuse

1.19 (0.79–1.80)

Differentiation

 Well

1

1

 Moderate

3.71 (1.65–8.38)

3.26 (1.42–7.48)

 Poor

3.53 (1.51–8.28)

3.48 (1.45–8.33)

T stage

 1

1

1

 2

1.91 (1.03–3.55)

2.10 (1.12–4.00)

 3

4.29 (2.39–7.69)

4.55 (2.49–8.31)

 4

5.40 (3.14–9.28)

4.96 (2.82–8.73)

N stage

 0

1

1

 1

1.72 (1.25–2.37)

2.08 (1.48–2.90)

 2

2.35 (1.74–3.19)

1.93 (1.40–2.65)

 3a

2.78 (2.03–3.80)

2.14 (1.55–2.95)

 3b

5.47 (3.80–7.86)

3.42 (2.32–5.06)

TNM stage

 I + II

1

 III

3.50 (2.78–4.39)

Histological type

 Adenocarcinoma

1

 Signet ring cell

0.92 (0.57–1.49)

 Mixed

1.05 (0.85–1.29)

Family history

 Yes

1

 No

0.72 (0.57–0.91)

Smoke

 No

1

1

 Yes

1.52(1.20–1.92)

1.43 (1.11–1.84)

Pre CRP/Alb ratio

  < 0.08

1

1

  ≥ 0.08

3.03 (2.45–3.74)

1.42 (1.08–1.87)

Post CRP/Alb ratio

  < 0.13

1

1

  ≥ 0.13

3.52 (2.84–4.37)

1.72 (1.29–2.30)

Pre Alb (g/L)

  < 35

1

  ≥ 35

0.25 (0.17–0.38)

Post Alb (g/L)

  < 35

1

1

  ≥ 35

0.21 (0.16–0.27)

0.47 (0.34–0.65)

Pre CRP (mg/L)

  ≤ 10

1

  > 10

5.91 (4.25–8.21)

Post CRP (mg/L)

  ≤ 10

1

1

  > 10

5.42 (4.10–7.17)

2.11 (1.49–3.00)