Table 4 Univariate and multivariate cox proportional hazard model of gastric cancer with OS

Age (year)

  < 60

1

  ≥ 60

1.02 (0.81–1.26)

Sex

 Male

1

 Female

0.74 (0.56–0.97)

Tumor location

 Upper third

1

 Middle third

1.05 (0.79–1.41)

Lower third

0.89 (0.68–1.17)

 Diffuse

1.82 (1.19–2.79)

Differentiation

 Well

1

1

 Moderate

2.66 (1.18–6.02)

1.42 (0.61–3.27)

 Poor

2.93 (1.24–6.91)

2.40 (0.99–5.79)

T stage

 1

1

1

 2

2.21 (1.04–4.70)

2.30 (1.07–4.94)

 3

3.09 (1.47–6.44)

2.76 (1.30–5.87)

 4

5.97 (3.07–11.64)

5.32 (2.67–10.60)

N stage

 0

1

1

 1

2.08 (1.45–2.99)

2.50 (1.69–3.70)

 2

2.49 (1.76–3.52)

2.35 (1.61–3.42)

 3a

3.11 (2.18–4.44)

2.71 (1.85–3.96)

 3b

6.00 (4.05–8.90)

4.71 (3.06–7.26)

TNM stage

 I + II

1

 III

3.91 (3.01–5.08)

Histological type

 Adenocarcinoma

1

1

 Signet ring cell

1.31 (0.80–2.15)

1.39 (0.83–2.33)

 Mixed

1.10 (0.88–1.39)

1.33 (1.04–1.71)

Family history

 Yes

1

 No

0.77 (0.60–0.99)

Smoke

 No

1

 Yes

1.44 (1.12–1.85)

Pre CRP/Alb ratio

  < 0.08

1

  ≥ 0.08

2.91 (2.32–3.66)

Post CRP/Alb ratio

  < 0.13

1

1

  ≥ 0.13

3.50 (2.77–4.41)

2.03 (1.55–2.66)

Pre Alb (g/L)

  < 35

1

  ≥ 35

0.15 (0.10–0.22)

Post Alb (g/L)

  < 35

1

1

  ≥ 35

0.12 (0.09–0.17)

0.34 (0.24–0.50)

Pre CRP (mg/L)

  ≤ 10

1

  > 10

8.63 (6.17–12.08)

1.61 (1.01–2.59)

Post CRP (mg/L)

  ≤ 10

1

1

  > 10

7.02 (5.27–9.35)

2.15 (1.37–3.39)