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Table 1 Characteristics of MCA atherosclerotic plaques with and without symptoms

From: Hemodynamics combined with inflammatory indicators exploring relationships between ischemic stroke and symptomatic middle cerebral artery atherosclerotic stenosis

 

Total (n = 32)

Symptomatic stenosis (n = 17)

Asymptomatic stenosis (n = 15)

P value

Age

57.1 ± 10.0

57.2 ± 9.9

57.0 ± 10.5

0.961

Sex (male)

17 (53.1%)

10 (58.8%)

7 (46.7%)

0.492

BMI

24.5 ± 3.6

23.1 ± 3.0

25.9 ± 3.7

0.026

Hypertension

20 (62.5%)

12 (70.6%)

8 (53.3%)

0.314

Diabetes

11 (34.4%)

7 (41.2%)

4 (26.7%)

0.388

Smoking

10 (31.3%)

4 (23.5%)

6 (40.0%)

0.316

Drinking

5 (15.6%)

3 (17.6%)

2 (13.3%)

0.737

Degree of stenosis

   

0.570

70–99%

20 (62.5%)

12 (70.6%)

8 (53.3%)

 

50–69%

9 (28.1%)

4 (23.5%)

5 (33.3%)

 

< 50%

3 (9.4%)

1 (5.9%)

2 (13.3%)

 

WBC (× 109/L)

7.2 ± 1.6

7.3 ± 1.6

7.2 ± 1.7

0.937

LYM (× 109/L)

2.0 ± 0.6

2.0 ± 0.7

2.1 ± 0.6

0.517

NEUT (× 109/L)

4.4 ± 1.3

4.5 ± 1.3

4.3 ± 1.4

0.749

MONO (× 109/L)

0.5 ± 0.2

0.5 ± 0.2

0.6 ± 0.2

0.842

Platelets (× 109/L)

245.5 ± 46.8

248.2 ± 45.9

242.5 ± 49.1

0.737

GLU(mmol/L)

5.5 (3.9–16.4)

5.6 (3.9–15.6)

5.1 (4.2–16.4)

0.100

Cholesterol (mmol/L)

4.9 ± 1.4

4.8 ± 1.7

5.1 ± 1.1

0.517

Triglyceride (mmol/L)

1.6 (0.6–4.3)

1.6 (0.6–3.9)

1.4 (0.8–4.3)

0.428

HDL (mmol/L)

1.1 ± 0.3

1.0 ± 0.3

1.2 ± 0.3

0.092

LDL (mmol/L)

3.2 ± 1.1

3.1 ± 1.4

3.3 ± 0.8

0.736

Apolipoprotein E (mg/L)

36.6 ± 11.0

35.6 ± 11.9

37.5 ± 10.2

0.662

hsCRP (mmol/L)

1.7 (0.2–26.9)

1.4 (0.2–18.3)

2.0 (0.3–26.9)

0.571

NLR

2.4 ± 1.1

2.6 ± 1.1

2.2 ± 1.0

0.418

LMR

4.1 ± 1.5

3.9 ± 1.6

4.2 ± 1.5

0.680

LMR ≤ 4.0 (%)

17 (53.1%)

11 (64.7%)

6 (40.0%)

0.162

PLR

133.4 ± 49.6

140.2 ± 49.9

125.8 ± 49.7

0.420

SII

603.1 ± 319.8

649.9 ± 315.5

550.1 ± 282.1

0.387

Plaque burden

0.8 ± 0.1

0.8 ± 0.1

0.8 ± 0.1

0.186

Plaque area (mm2)

13.2 ± 6.9

14.3 ± 7.3

12.0 ± 6.5

0.360

Plaque enhancement

21 (65.6%)

14 (82.4%)

7 (46.7%)

0.034

CR

0.54 ± 0.14

0.56 ± 0.12

0.52 ± 0.13

0.486

WSSmax (Pa)

258.1 ± 142.0

324.0 ± 146.8

184.5 ± 93.6

0.003

WSSR

85.0 ± 54.2

112.8 ± 51.3

53.5 ± 38.8

0.001

PR

0.7 ± 0.2

0.6 ± 0.2

0.7 ± 0.2

0.004

Hospitalization days

10.4 ± 5.4

12.7 ± 6.0

7.7 ± 3.2

0.008

  1. MCA middle cerebral arterial, BMI body mass index, WBC white blood cells, LYM lymphocyte counts, NEUT neutral counts, MONO monocyte counts, CRP C-reactive protein, NLR neutrophil-to-lymphocyte ratio, LMR lymphocyte-to-monocyte ratio, PLR platelet-to-lymphocyte ratio, SII systemic immune-inflammation index, CR the plaque-to-pituitary stalk contrast ratio, WSSmax the maximum wall shear stress, WSSR WSS ratio, PR pressure ratio