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Fig. 2 | European Journal of Medical Research

Fig. 2

From: Prediction of survival and immunotherapy response by the combined classifier of G protein-coupled receptors and tumor microenvironment in melanoma

Fig. 2

Establishment of GPCR score for melanoma and pan-cancers at bulk level. A Validation of prognostic GPCRs using LASSO regression analysis. B LASSO coefficient profile plot of prognostic GPCRs. C Multivariate Cox regression analysis with a bootstrap algorithm screening of 12 prognostic GPCRs. D Kaplan–Meier survival curves of the TCGA–SKCM cohort in patients with melanoma with high-GPCR score vs. low-GPCR score. E Validation of role of GPCR score in pan-cancers. F Decoding the different immune microenvironments of two GPCR groups using CIBERSORT. GPCR G protein-coupled receptor; LASSO least absolute shrinkage and selection operator; TCGA The Cancer Genome Atlas; SKCM Skin cutaneous melanoma

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European Journal of Medical Research

ISSN: 2047-783X

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