Table 2 Correlation between SAMD13 expression level and gene markers of tumor infiltrating immune cells in TCGA–LIHC
From: SAMD13 serves as a useful prognostic biomarker for hepatocellular carcinoma
Immune cell | Biomarker | R value | p value |
|---|---|---|---|
B cell | CD19 | 0.15 | ** |
CD79A | 0.1 | * | |
T cell (general) | CD3D | 0.19 | *** |
CD3E | 0.17 | *** | |
CD2 | 0.17 | ** | |
CD8+ T cell | CD8A | 0.13 | * |
CD8B | 0.14 | ** | |
CD4+ T cell | CD4 | 0.14 | ** |
TAM | CCL3 | 0.058 | n.s |
CD68 | 0.21 | *** | |
IL10 | 0.22 | *** | |
M1 macrophage | NOS2 | 0.080 | n.s |
IRF5 | 0.28 | *** | |
PTGS2 | 0.21 | *** | |
M2 macrophage | CD163 | 0.14 | ** |
VSIG4 | 0.23 | *** | |
MS4A4A | 0.19 | *** | |
Neutrophil | CEACAM8 | 0.04 | n.s |
ITGAM | 0.28 | *** | |
CCR7 | 0.12 | * | |
Natural killer cell | KIR2DL4 | 0.052 | n.s |
KIR2DL3 | 0.005 | n.s | |
KIR3DL3 | −0.02 | n.s | |
KIR3DL2 | 0.075 | n.s | |
KIR2DS4 | −0.05 | n.s | |
KIR2DL1 | 0.012 | n.s | |
KIR3DL1 | −0.066 | n.s | |
Dendritic cell | HLA–DPB1 | 0.2 | *** |
HLA–DQB1 | 0.073 | n.s | |
HLA–DRA | 0.2 | *** | |
HLA–DPA1 | 0.2 | *** | |
CD1C | 0.2 | *** | |
NRP1 | 0.22 | *** | |
ITGAX | 0.29 | *** | |
Th1 | TBX21 | 0.096 | n.s |
STAT4 | 0.19 | *** | |
STAT1 | 0.23 | *** | |
IFNG | 0.11 | * | |
TNF | 0.24 | *** | |
Th2 | GATA3 | 0.21 | *** |
STAT6 | 0.2 | *** | |
IL13 | 0.052 | n.s | |
STAT5A | 0.17 | *** | |
Tfh | BCL6 | 0.087 | n.s |
IL21 | 0.021 | n.s | |
Th17 | STAT3 | 0.18 | *** |
IL17A | 0.044 | n.s | |
Treg | FOXP3 | 0.097 | n.s |
CCR8 | 0.25 | *** | |
TGFB1 | 0.27 | *** | |
STAT5B | 0.15 | *** | |
T cell exhaustion | PDCD1 | 0.14 | ** |
CTLA4 | 0.2 | *** | |
LAG3 | 0.069 | n.s | |
HAVCR2 | 0.26 | *** | |
GZMB | −0.015 | n.s |