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Table 3 CpGs with methylation across the patients with TCGA–LIHC

From: SAMD13 serves as a useful prognostic biomarker for hepatocellular carcinoma

CpG

Chromosome

Start

End

UCSC_RefGene_Group

Relation_to_UCSC_CpG_Island

Overall Survival (beta-value) Median Cutoff (50%)

HR

95% CI

p value

cg20426713

chr1

84297655

84297656

TSS1500

N_Shore

0.86

0.61–1.21

0.386

cg11555919

chr1

84298249

84298250

TSS200

N_Shore

0.8

0.57–1.12

0.196

cg24002839

chr1

84298595

84298596

Body

Island

0.87

0.62–1.23

0.437

cg16026299

chr1

84298692

84298693

Body

Island

1.32

0.94–1.85

0.112

cg15103960

chr1

84299021

84299022

Body

Island

0.71

0.51–1

0.052

cg02041547

chr1

84299222

84299223

Body

Island

0.46

0.32–0.64

 < 0.001

cg23694882

chr1

84300841

84300842

TSS1500;Body

S_Shore

1.52

1.08–2.14

0.016

cg17142950

chr1

84301099

84301100

TSS1500;Body

S_Shore

1.04

0.74–1.46

0.838

cg19869443

chr1

84301138

84301139

TSS1500;Body

S_Shore

0.94

0.67–1.33

0.731

cg23086720

chr1

84301641

84301642

1stExon;TSS1500;5'UTR;Body

S_Shelf

0.51

0.36–0.72

 < 0.001

cg20466954

chr1

84302676

84302677

1stExon;5'UTR;Body

S_Shelf

0.93

0.66–1.31

0.691

cg13305246

chr1

84303019

84303020

5'UTR;Body

S_Shelf

1.05

0.75–1.48

0.762

cg15089272

chr1

84329844

84329845

Body

OpenSea

1.5

1.07–2.12

0.019

cg22529952

chr1

84347529

84347530

Body

OpenSea

1.27

0.9–1.79

0.171

cg23925111

chr1

84350246

84350247

3'UTR

OpenSea

1.62

1.15–2.27

0.006

  1. CpG (CpG ID), UCSC_RefGene_Name (gene name, based on UCSC annotations); UCSC_RefGene_Group (gene region, based on UCSC annotations); Relation_to_UCSC_CpG_Island (island region, based on UCSC annotations); Regulatory_Feature_Group (type of regulatory region, based on EPIC manifest annotations). Bold font indicates statistical significance