Table 1 Clinicopathological characteristics of RC patients
Factors | Define | Train (N = 16,580) | Test (N = 7100) | All (N = 23,680) | Statistic | P |
|---|---|---|---|---|---|---|
Age (years) | 63.02 ± 13.38 | 62.90 ± 13.41 | 62.98 ± 13.39 | 0.652 | 0.514 | |
Time (years) | 52.35 ± 27.20 | 52.53 ± 27.77 | 52.41 ± 27.93 | − 0.456 | 0.648 | |
Marriage | Married | 9830 (59.3) | 4192 (59) | 14,022 (59.2) | 0.81 | 0.981 |
Single | 2827 (17.1) | 1211 (17.1) | 4038 (17.1) | |||
Widowed | 1902 (11.5) | 825 (11.6) | 2727 (11.5) | |||
Other | 2021 (12.2) | 872 (12.3) | 2893 (12.2) | |||
Race | White | 13,513 (81.5) | 5787 (81.5) | 19,300 (81.5) | 2.516 | 0.284 |
Black | 1416 (8.5) | 572 (8.1) | 1988 (8.4) | |||
Other | 1651 (10) | 741 (10.4) | 2392 (10.1) | |||
Sex | Female | 6649 (40.1) | 2869 (40.4) | 9518 (40.2) | 0.194 | 0.66 |
Male | 9931 (59.9) | 4231 (59.6) | 14,162 (59.8) | |||
Deposits | Yes | 970 (5.9) | 423 (6) | 1393 (5.9) | 0.449 | 0.799 |
No | 11,545 (69.6) | 4913 (69.2) | 16,458 (69.5) | |||
Others | 4065 (24.5) | 1764 (24.8) | 5829 (24.6) | |||
Behav | Behav1 | 11,851 (71.5) | 5029 (70.8) | 16,880 (71.3) | 1.973 | 0.578 |
Behav2 | 1383 (8.3) | 592 (8.3) | 1975 (8.3) | |||
Behav3 | 1630 (9.8) | 739 (10.4) | 2369 (10) | |||
Other | 1716 (10.3) | 740 (10.4) | 2456 (10.4) | |||
Grade | I | 1457 (8.8) | 622 (8.8) | 2079 (8.8) | 0.073 | 0.964 |
II | 12,812 (77.3) | 5479 (77.2) | 18,291 (77.2) | |||
III、IV | 2311 (13.9) | 999 (14.1) | 3310 (14) | |||
AJCC Stage | I | 4803 (29) | 2106 (29.7) | 6909 (29.2) | 2.562 | 0.464 |
II | 4096 (24.7) | 1692 (23.8) | 5788 (24.4) | |||
III | 5849 (35.3) | 2526 (35.6) | 8375 (35.4) | |||
IV | 1832 (11) | 776 (10.9) | 2608 (11) | |||
T Stage | T1 | 3250 (19.6) | 1468 (20.7) | 4718 (19.9) | 4.120 | 0.249 |
T2 | 2882 (17.4) | 1191 (16.8) | 4073 (17.2) | |||
T3 | 8905 (53.7) | 3784 (53.3) | 12,689 (53.6) | |||
T4 | 1543 (9.3) | 657 (9.3) | 2200 (9.3) | |||
N Stage | N0/N1 | 14,733 (88.9) | 6274 (88.4) | 21,007 (88.7) | 1.211 | 0.271 |
N2 | 1847 (11.1) | 826 (11.6) | 2673 (11.3) | |||
M Stage | M0 | 14,748 (89) | 6324 (89.1) | 21,072 (89) | 0.073 | 0.787 |
M1 | 1832 (11) | 776 (10.9) | 2608 (11) | |||
Surgery | No | 2291 (13.8) | 1011 (14.2) | 3302 (13.9) | 0.736 | 0.391 |
Yes | 14,289 (86.2) | 6089 (85.8) | 20,378 (86.1) | |||
LNSur | No | 4572 (27.6) | 1990 (28) | 6562 (27.7) | 0.681 | 0.711 |
Yes | 11,853 (71.5) | 5040 (71) | 16,893 (71.3) | |||
Unknown | 155 (0.9) | 70 (1) | 225 (1) | |||
Radiation | Yes | 9618 (58) | 4143 (58.4) | 13,761 (58.1) | 0.240 | 0.625 |
No | 6962 (42) | 2957 (41.6) | 9919 (41.9) | |||
Chemotherapy | Yes | 10,739 (64.8) | 4649 (65.5) | 15,388 (65) | 1.095 | 0.295 |
No | 5841 (35.2) | 2451 (34.5) | 8292 (35) | |||
CEA | Yes | 4492 (27.1) | 1966 (27.7) | 6458 (27.3) | 0.993 | 0.609 |
No | 5911 (35.7) | 2524 (35.5) | 8435 (35.6) | |||
Others | 6177 (37.3) | 2610 (36.8) | 8787 (37.1) | |||
Brain | No | 16,559 (99.9) | 7096 (99.9) | 23,655 (99.9) | 2.331 | 0.127 |
Yes | 21 (0.1) | 4 (0.1) | 25 (0.1) | |||
Positive | No | 7889 (47.6) | 3370 (47.5) | 11,259 (47.5) | 0.486 | 0.784 |
Yes | 4184 (25.2) | 1771 (24.9) | 5955 (25.1) | |||
Other | 4507 (27.2) | 1959 (27.6) | 6466 (27.3) | |||
Liver | No | 15,320 (92.4) | 6578 (92.6) | 21,898 (92.5) | 0.437 | 0.508 |
Yes | 1260 (7.6) | 522 (7.4) | 1782 (7.5) | |||
Lung | No | 16,031 (96.7) | 6862 (96.6) | 22,893 (96.7) | 0.026 | 0.872 |
Yes | 549 (3.3) | 238 (3.4) | 787 (3.3) | |||
Bone | No | 16,476 (99.4) | 7064 (99.5) | 23,540 (99.4) | 1.222 | 0.269 |
Yes | 104 (0.6) | 36 (0.5) | 140 (0.6) | |||
Size(cm) | < 3 | 5124 (30.9) | 2215 (31.2) | 7339 (31) | 0.278 | 0.87 |
3–5 | 5304 (32) | 2250 (31.7) | 7554 (31.9) | |||
5– | 6152 (37.1) | 2635 (37.1) | 8787 (37.1) | |||
Malignant | 1 | 12,405 (74.8) | 5379 (75.8) | 17,784 (75.1) | 2.440 | 0.295 |
2 | 3224 (19.4) | 1335 (18.8) | 4559 (19.3) | |||
3– | 951 (5.7) | 386 (5.4) | 1337 (5.6) | |||
Status | 0 | 10,130 (61.1) | 4376 (61.6) | 14,506 (61.3) | 0.693 | 0.707 |
1 | 4602 (27.8) | 1935 (27.3) | 6537 (27.6) | |||
2 | 1848 (11.1) | 789 (30) | 2637 (11.1) |