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Fig. 3 | European Journal of Medical Research

Fig. 3

From: LncRNA SNHG6 role in clinicopathological parameters in cancers

Fig. 3

Diagram regarding the role of SNHG6 in the regulation of hallmarks of cancer. SNHG6 interacts with different miRNAs and activates the downstream signaling pathways;  this results in the perturbation in the signaling cascade resulting in uncontrolled cell differentiation, proliferation, tumorigenesis, inhibition of apoptosis, increase migration and metastasis. ↑increase, ↓decrease; enhancer of zeste homolog 2 (EZH2), nuclear cap-binding subunit 3 (NCBP3), LIM domain only 3 (LMO3), flotillin-1 (FLOT1), homeobox protein GBX-2 (GBX2), histone 3 lysine 27 trimethylation (H3K27me3), matrix metalloproteinases (MMP), mitogen-activated protein kinase 6 (MAPK6), vasodilator-stimulated phosphoprotein (VASP), laminin subunit gamma-1 (LAMC1), small nucleolar RNA host gene 6 (SNHG6)

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