Fig. 4
From: SNAP25 is a potential target for early stage Alzheimer’s disease and Parkinson’s disease
Validation of five hub genes in 6-month AD and PD mice samples. The mRNA levels of five hub genes were validated in 6-month AD+/PD+ mice samples and age-matched control mice samples by real-time qPCR. Five hub genes include VAMP2, SNAP25, SYT1, SYN1, NSF, and STX1A. All hub genes significantly declined in both AD+/PD+ mice samples, compared to those in control samples (AD− and PD−). Relative quantification (RQ) values were calculated. Data are the mean ± s.e.m from 8 mice in each group. A T test was used to analyze the difference between the two groups. *0.01 ≤ P < 0.05, **0.001 ≤ P < 0.01, ***P < 0.001