Table 4 Results of the synthetic knowledge synthesis

Synthesis and regulatory mechanisms of breast cancer-related proteins

Yellow

Translation (350), activation (254), messenger RNA (225), phosphorylation (198), pathway (151), translation initiation (123), mTOR (107), mammalian target (85), c-myc (75), kinase (68), protein synthesis (67), eIF 4 E (66), initiation (66), cyclin d 1 (65), mechanism (63)

Regulation of Protein Synthesis, mRNA Regulation and Translation Activation, Impact of Protein Synthesis in Breast Cancer Progression, Molecular Mechanisms and Signaling Pathways

Protein Synthesis and Cellular Processes in Breast Cancer Progression and Metastasis

Blue

Growth (274), proliferation (259), cells (232), metastasis (174), inhibition (155), progression (133), survival (125), resistance (118), overexpression (105), invasion (98), migration (82), angiogenesis (75), microRNA (71), differentiation (70), prognosis (65)

Cellular Processes in Breast Cancer Progression, Protein Synthesis and Cancer Cell Survival, Protein Synthesis and Differentiation, Prognostic Factors in Breast Cancer, Inhibition of Protein Synthesis in Breast Cancer

Apoptotic Regulation and Related Cancer Research in Breast Cancer Cells

Green

Breast cancer (1339), apoptosis (314), gene expression (302), breast cancer cells (169), in vitro (154), prostate cancer (114), in vivo (92), lung cancer (90), down-regulation (88), p 53 (81), up-regulation (66), ovarian cancer (65), risk (65), tumor suppressor (63), colorectal-cancer (59), oxidative stress (58)

Mechanisms of Apoptosis in Breast Cancer Cells, p53 Tumor Suppressor Function in Breast Cancer, Comparative Apoptosis Studies Across Different Cancer Types, Oxidative Stress and Breast Cancer Risk

Association of protein expression with breast cancer development

Red

Expression (831), cancer (407), protein (358), biosynthesis (124), breast (123), gene (205), identification (192), metabolism (120), binding (80), receptor (100), therapy (87), transcription (83), mechanisms (77), target (63), mutations (59), estrogen (58)

Protein Expression and Biosynthesis in Breast Cancer, Mechanisms of Protein Regulation in Breast Cancer, Protein Metabolism and Binding in Breast Cancer, Therapeutic Targeting of Protein Expression in Breast Cancer