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Table 1 Demographic and clinical characteristics of the study population

From: Influence of perioperative blood pressure regulation on postoperative delirium in patients undergoing head and neck free flap reconstruction

Variable

Non-POD (n = 55)

POD (n = 55)

p-value

Sex (n)

 Male

32 (58.2%)

37 (67.3%)

0.486

 Female

23 (41.8%)

18 (32.7%)

Age (years)

65.0 (20.0)

73.0 (16.0)

0.011

BMI (kg/m2)

25.3 (7.3)

24.3 (5.9)

0.206

ASA (n)

 1 + 2

37 (67.3%)

26 (47.3%)

0.063

 3 + 4

18 (32.7%)

29 (52.7%)

Excessive alcohol consumption (n)

11 (20.0%)

17 (30.9%)

0.307

Smoking (n)

19 (34.5%)

25 (45.5%)

0.307

Preoperative arterial hypertension (n)

28 (50.9%)

29 (52.7%)

1.000

Preoperative antihypertensive medication (n)

 ACE inhibitors

16 (29.1%)

10 (18.2%)

0.238

 AT antagonists

6 (10.9%)

13 (23.6%)

0.118

 ß-blockers

10 (18.2%)

18 (32.7%)

0.170

 Calcium antagonists

4 (7.3%)

7 (12.7%)

0.549

 Diuretics

8 (14.5%)

14 (25.5%)

0.263

Transplant type (n)

 Radial forearm flap

24 (43.6%)

24 (43.6%)

 = 

 Anterolateral thigh flap

25 (45.5%)

25 (45.5%)

 Fibular flap

3 (5.5%)

3 (5.5%)

 Iliac crest flap

1 (1.8%)

1 (1.8%)

 Lower leg perforator flap

1 (1.8%)

1 (1.8%)

 Latissimus flap

1 (1.8%)

1 (1.8%)

Transplant location (n)

 Floor of mouth

7 (12.7%)

7 (12.7%)

 = 

 Tongue

7 (12.7%)

7 (12.7%)

 Mandibula

19 (34.5%)

19 (34.5%)

 Maxilla

8 (14.5%)

8 (14.5%)

 Soft palate

4 (7.3%)

4 (7.3%)

 Cheek

3 (5.5%)

3 (5.5%)

 Extraoral

7 (12.7%)

7 (12.7%)

Tracheotomy (n)

 No

9 (16.4%)

9 (16.4%)

 = 

 Yes

46 (83.6%)

46 (83.6%)

Operation time (min)

581.0 (150.0)

611.0 (183.0)

0.580

Blood transfusion (n)

 No

36 (65.5%)

42 (76.4%)

0.327

 Yes

19 (34.5%)

13 (23.6%)

Transplant revision (n)

 No

52 (94.5%)

38 (69.1%)

 < 0.001

 Yes

3 (5.5%)

17 (30.9%)

Transplant success (n)

 No

1 (1.8%)

2 (3.6%)

1.000

 Yes

54 (98.2%)

53 (96.4%)

Duration of hospital stay (days)

17 (10)

23 (22)

 < 0.001

Duration of ICU stay (days)

2 (1)

7 (11)

 < 0.001

Postoperative Complications (n)

 No

54 (98.2%)

36 (65.5%)

 < 0.001

 Yes

1 (1.8%)

19 (34.5%)

  1. Demographic and clinical parameters are indicated as numbers (with percentage) or median (with interquartile range) (separately described for the group of patients without POD (non-POD) and the group of patients with POD (POD)); p-values corresponding to testing for differences between the group of patients without POD and patients with POD with McNemar test (sex, ASA, excessive alcohol consumption, smoking, preoperative arterial hypertension, ACE inhibitors, AT antagonists, ß-blockers, diuretics, blood transfusion, calcium antagonists, transplant revision, transplant success, postoperative complications) and Wilcoxon signed rank test (age, BMI, operation time, duration of hospital stay, duration of ICU stay); significant p-values are bold; = patients without POD and patients with POD are matched
  2. POD postoperative delirium, BMI body mass index, ASA American Society of Anesthesiologists score, ICU intensive care unit