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Table 1 Clinical and demographic characteristics of participants infected during delta- and omicron-driven surges

From: Clinical and experimental evidence suggest omicron variant of SARS-CoV-2 is inherently less pathogenic than delta variant independent of previous immunity

Characteristic

Delta cohort, N = 3292

Omicron cohort, N = 2998

P value

Age

35 (28, 45)

32 (26, 42)

P < 0.01

Sex

  

P = 0.14

 Female

1,099 (33%)

1089 (36%)

 

 Male

2,193 (67%)

1,909 (64%)

 

Vaccination status

  

P < 0.001

 Both Doses

234 (7.1%)

2,386 (80%)

 

 Single dose

588 (18%)

471 (16%)

 

 Unvaccinated

2,470 (75%)

141 (4%)

 

Booster dose

0 (0%)

65 (2.7%)

 

Risk of occupational exposure

  

P < 0.001

 Defense Staff

123 (3.7%)

98 (3.3%)

 

 Essential Services

90 (2.7%)

59 (2.0%)

 

 Hospital Staff

229 (7.0%)

319 (11%)

 

 Municipal Worker

54 (1.6%)

38 (1.3%)

 

 None

2796 (85%)

2,484 (83%)

 

Fever

2460 (74.7%)

1329 (44.3%)

P < 0.001

Cough

1210 (36.7%)

1456 (48.56%)

P < 0.001

Sore throat

1210 (36.7%)

1032 (34.4%)

P < 0.001

Breathlessness

506 (15.3%)

117 (3.9%)

P < 0.001

Headache

859 (26.1%)

412 (13.7%)

P < 0.001

Gastrointestinal symptom

463 (14.1%)

39 (1.3%)

P < 0.001

Comorbidity

408 (12.4%)

225 (7.5%)

P < 0.001

Hospitalisation

167 (5.1%)

9 (0.3%)

P < 0.001

Hospitalised subjects

N = 167

N = 9

P < 0.001

Days of Hospitalisation

9.0 (5.0, 10.0)

4.0 (3.0, 5.0)

P < 0.001

Oxygen Supplementation

99 (54%)

6 (66.7%)

P < 0.001

Duration of oxygen therapy

7.5 (5.0, 12.0)

6.0 (4.2, 9.2)

P < 0.001

ICU admission

28 (17%)

0 (0%)

P < 0.001

Duration of ICU stay

5 (2.5,7.0)

aNot applicable

 

Ventilator support (N)

5 (3%)

0 (0%)

P < 0.001

Duration of ventilator support

3 (1.0, 9.5)

aNot applicable

 

Death

12 (0.4%)

0 (0%)

P < 0.001

  1. aNo comparator available