Table 1 Demographic characteristics of the study population before matching (n = 4600)
Before matching | After matching | |||||
|---|---|---|---|---|---|---|
DOR (n = 365) | NOR (n = 4235) | P-value | DOR (n = 365) | NOR (n = 1440) | P-value | |
Mean ± SD/n (%) | Mean ± SD/n (%) | Mean ± SD/n (%) | Mean ± SD/n (%) | |||
Female age (years) | 30.93 ± 2.89 | 29.89 ± 3.05 | < 0.01** | 30.93 ± 2.89 | 30.88 ± 2.80 | 0.73 |
Male age (years) | 33.05 ± 4.04 | 31.67 ± 3.71 | < 0.01** | 33.05 ± 4.04 | 32.85 ± 3.86 | 0.37 |
BMI (kg/m2) | 22.60 ± 3.80 | 22.86 ± 3.95 | 0.24 | 22.60 ± 3.80 | 22.61 ± 3.73 | 0.98 |
Infertility duration | 3.29 ± 2.12 | 3.25 ± 2.02 | 0.74 | 3.29 ± 2.12 | 3.44 ± 2.16 | 0.24 |
Sex hormone levels | ||||||
AMH (ng/ml) | 0.77 ± 0.27 | 5.45 ± 3.77 | < 0.01** | 0.77 ± 0.27 | 5.17 ± 3.53 | < 0.01** |
FSH (IU/L) | 7.93 ± 3.68 | 6.39 ± 3.23 | < 0.01** | 7.93 ± 3.68 | 6.52 ± 3.83 | < 0.01** |
LH (IU/L) | 4.71 ± 8.29 | 5.66 ± 5.33 | 0.03* | 4.71 ± 8.29 | 5.69 ± 5.63 | < 0.01** |
E2 (pmol/L) | 47.41 ± 35.35 | 49.37 ± 51.74 | 0.45 | 47.41 ± 35.35 | 51.52 ± 52.87 | 0.16 |
T (ng/ml) | 0.88 ± 3.19 | 0.61 ± 2.25 | 0.04* | 0.88 ± 3.19 | 0.64 ± 2.20 | 1.00 |
Infertility diagnosis | < 0.01** | < 0.01** | ||||
Uterine | 11 (3.0) | 893 (21.1) | 11 (3.0) | 358 (24.9) | ||
Ovulatory | 21 (5.8) | 683 (16.1) | 21 (5.8) | 224 (15.6) | ||
Endometriosis | 9 (2.5) | 96 (2.3) | 9 (2.5) | 33 (2.3) | ||
Male factor | 106 (29.0) | 1832 (43.3) | 106 (29.0) | 561 (39.0) | ||
Unexplained | 24 (6.6) | 731 (17.3) | 24 (6.6) | 264 (18.3) | ||
Decreased ovarian reserve | 194 (53.2) | –0 | 194 (53.2) | 0 | ||
AFC | 5.18 ± 5.51 | 11.80 ± 7.28 | < 0.01** | 5.18 ± 5.51 | 11.01 ± 6.72 | < 0.01** |
Seminal parameters | ||||||
Sperm concentration, *106/ml | 66.83 ± 28.86 | 69.52 ± 31.86 | 0.12 | 66.83 ± 28.86 | 68.85 ± 33.50 | 0.29 |
Sperm progressive motility (%) | 33.69 ± 18.34 | 33.66 ± 17.88 | 0.97 | 33.69 ± 18.34 | 33.56 ± 17.41 | 0.90 |
Endometrial thickness (mm) | 10.30 ± 3.41 | 10.68 ± 3.64 | 0.06 | 10.30 ± 3.41 | 10.91 ± 3.73 | < 0.01** |
COH protocol | < 0.01** | < 0.01** | ||||
Natural cycle | 127 (34.8) | 1391 (32.8) | 127 (34.8) | 499 (34.7) | ||
Clomiphene | 42 (11.5) | 841 (19.9) | 42 (11.5) | 298 (20.7) | ||
Letrozole | 145 (39.7) | 1346 (31.8) | 145 (39.7) | 405 (28.1) | ||
Gn | 51 (14.0) | 657 (15.5) | 51 (14.0) | 238 (16.5) | ||