Coagulation parameters for the differential diagnosis of pancreatic cancer in the early stage: a retrospective study

Table 3 Differential value of coagulation indexes for PC based on ROC curve

	Optimal Cutpoint	Sensitivity	Specificity	PPV	NPV	Positive LR	Negative LR	AUC	Accuracy
(1)
PT(s)	12.85	0.912	0.162	0.731	0.423	1.088	0.545	0.506	0.697
APTT(s)	28.25	0.747	0.500	0.789	0.442	1.494	0.506	0.666	0.676
FIB(g/L)	2.7	0.841	0.618	0.846	0.609	2.200	0.257	0.737	0.777
TT(s)	17.65	0.488	0.676	0.790	0.346	1.509	0.757	0.587	0.542
DD2(mg/L)	0.235	0.835	0.426	0.785	0.509	1.456	0.386	0.654	0.718
PLT(10^9/L)	244.5	0.241	0.838	0.788	0.306	1.491	0.905	0.494	0.412
R(min)	5.05	0.482	0.794	0.854	0.380	2.343	0.652	0.628	0.571
K(min)	1.65	0.447	0.779	0.835	0.361	2.027	0.709	0.619	0.542
Angle(deg)	68.55	0.412	0.838	0.864	0.363	2.545	0.702	0.627	0.534
MA(mm)	66.95	0.312	0.912	0.898	0.346	3.533	0.755	0.602	0.483
CI	1.55	0.388	0.897	0.904	0.370	3.772	0.682	0.648	0.534
LY30(%)	0.15	0.429	0.750	0.811	0.345	1.718	0.761	0.575	0.521

	Optimal Cutpoint	Sensitivity	Specificity	PPV	NPV	Positive LR	Negative LR	AUC	Accuracy
(2)
PT(s)	11.25	0.248	0.868	0.743	0.428	1.871	0.867	0.562	0.491
APTT(s)	26.75	0.505	0.779	0.779	0.505	2.288	0.635	0.671	0.613
FIB(g/L)	2.7	0.790	0.618	0.761	0.656	2.067	0.339	0.723	0.723
TT(s)	17.85	0.571	0.588	0.682	0.471	1.388	0.729	0.565	0.578
DD2(mg/L)	0.255	0.790	0.471	0.697	0.593	1.493	0.445	0.635	0.665
PLT(10^9/L)	244.5	0.248	0.838	0.703	0.419	1.531	0.898	0.526	0.480
R(min)	5.05	0.486	0.794	0.785	0.500	2.359	0.648	0.621	0.607
K(min)	1.65	0.467	0.779	0.766	0.486	2.116	0.684	0.621	0.590
Angle(deg)	68.55	0.448	0.838	0.810	0.496	2.767	0.659	0.630	0.601
MA(mm)	65.35	0.429	0.824	0.789	0.483	2.429	0.694	0.614	0.584
CI	1.55	0.410	0.897	0.860	0.496	3.978	0.658	0.648	0.601
LY30(%)	0.15	0.390	0.750	0.707	0.443	1.562	0.813	0.554	0.532

PPV represents positive predictive value, NPV represents Negative Predictive Value. LR represents likelihood ratio, AUC represents Area Under Curve

ISSN: 2047-783X